Artificial endocrine pancreas and optimal blood glucose regulation in diabetic patients — from bedside-type to wearable-type

The artificial endocrine pancreas is a feedback control system regulating insulin delivery on a minute-by-minute basis according to the measured blood glucose levels. The bedside-type artificial endocrine pancreas has been proven to be useful not only as a therapeutic tool for diabetes mellitus but...

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Veröffentlicht in:Diabetes research and clinical practice 1994-10, Vol.24, p.S251-S259
Hauptverfasser: Shichiri, Motoaki, Kishikawa, Hideki, Sakakida, Michiharu, Kajiwara, Kenichiro, Hashiguchi, Yasuhiro, Nishida, Kenro, Uemura, Takero, Konno, Yumi, Ichinose, Kenshi
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container_end_page S259
container_issue
container_start_page S251
container_title Diabetes research and clinical practice
container_volume 24
creator Shichiri, Motoaki
Kishikawa, Hideki
Sakakida, Michiharu
Kajiwara, Kenichiro
Hashiguchi, Yasuhiro
Nishida, Kenro
Uemura, Takero
Konno, Yumi
Ichinose, Kenshi
description The artificial endocrine pancreas is a feedback control system regulating insulin delivery on a minute-by-minute basis according to the measured blood glucose levels. The bedside-type artificial endocrine pancreas has been proven to be useful not only as a therapeutic tool for diabetes mellitus but also as an elegant research tool for investigating the pathophysiology of the disease. With significant advances in the development of a subcutaneous tissue glucose monitoring system, the wearable-type artificial endocrine pancreas has been applied to diabetic patients. With this system, perfect glycemic control can be obtained for longer periods in ambulatory diabetic patients. The trend in the development of the artificial endocrine pancreas is now directed to implantable devices. Much efforts have been conducted to realize these devices.
doi_str_mv 10.1016/0168-8227(94)90258-5
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Bedside-type artificial endocrine pancreas
Biocompatible membrane
Blood Glucose - analysis
Blood Glucose Self-Monitoring
Diabetes Mellitus - blood
Diabetes Mellitus - drug therapy
Diabetes Mellitus - epidemiology
Humans
Infusion Pumps, Implantable
Insulin - administration & dosage
Insulin - therapeutic use
Insulin Infusion Systems - standards
Insulin Infusion Systems - trends
Japan - epidemiology
Microdialysis sampling method
Needle-type glucose sensor
Wearable-type artificial endocrine pancreas
title Artificial endocrine pancreas and optimal blood glucose regulation in diabetic patients — from bedside-type to wearable-type
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