2,4-D and alkaloid accumulation in periwinkle cell suspensions
Omission of 2,4-D from culture medium during one subculture of Catharanthus roseus cells, strain C20, resulted in an increased alkaloid accumulation, without effect on growth. Alkaloid accumulation, rather than growth, seemed to be more sensitive to 2,4-D. 2,4-D inhibited alkaloid accumulation essen...
Gespeichert in:
| Veröffentlicht in: | Biochimie 1994, Vol.76 (5), p.410-416 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 416 |
|---|---|
| container_issue | 5 |
| container_start_page | 410 |
| container_title | Biochimie |
| container_volume | 76 |
| creator | Arvy, M.P. Imbault, N. Naudascher, F. Thiersault, M. Doireau, P. |
| description | Omission of 2,4-D from culture medium during one subculture of
Catharanthus roseus cells, strain C20, resulted in an increased alkaloid accumulation, without effect on growth. Alkaloid accumulation, rather than growth, seemed to be more sensitive to 2,4-D. 2,4-D inhibited alkaloid accumulation essentially during growth phase, but its inhibitory effect during this period was partially reversible. As this reversibility was underlined only during the stationary phase, this suggested that this action could be situated upstream in a terpenoid non-specific pathway. 2,4-D feeding showed that inhibition is weaker and weaker as the alkaloid accumulation period proceeds. Auxin action during this period could take place downstream in specific alkaloid pathways. The lower alkaloid accumulation obtained after loganic acid feeding compared to that obtained with secologanin and loganin could indicate that loganic acid methylation should be one of the 2,4-D target(s). |
| doi_str_mv | 10.1016/0300-9084(94)90117-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77726492</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0300908494901171</els_id><sourcerecordid>77726492</sourcerecordid><originalsourceid>FETCH-LOGICAL-c376t-eaa7744358c40513e425e6d5b0afd325a677f359bb0e2114fc27fa97f5e327723</originalsourceid><addsrcrecordid>eNp9kF1LwzAUhoMoc07_gCj0ShSsJk3SNDcDmU6FgSB6HdL0VOL6MZNW8d-b0rFL4UAOPO85JzwInRF8QzBJbzHFOJY4Y5eSXUlMiIjJHpqSlGZxSjK6j6a7yCE68v4TY8xxIidoIjImCRZTNE-uWXwf6aaIdLXWVWtDY0xf95XubNtEtok24OyPbdYVRAaqKvK930DjA_XH6KDUlYeT7TtD78uHt8VTvHp5fF7crWJDRdrFoLUQjFGeGYY5ocASDmnBc6zLgiZcp0KUlMs8x5AQwkqTiFJLUXKgiRAJnaGLce_GtV89-E7V1g-f0Q20vVcihFImhyAbg8a13jso1cbZWrtfRbAatKnBiRqcKBlq0KZIGDvf7u_zGord0NZT4KcjL3Wr9IezXi1fZZDJJA9wPkIIBr4tOOWNhcZAYR2YThWt_f_6H3SLgnQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77726492</pqid></control><display><type>article</type><title>2,4-D and alkaloid accumulation in periwinkle cell suspensions</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Arvy, M.P. ; Imbault, N. ; Naudascher, F. ; Thiersault, M. ; Doireau, P.</creator><creatorcontrib>Arvy, M.P. ; Imbault, N. ; Naudascher, F. ; Thiersault, M. ; Doireau, P.</creatorcontrib><description>Omission of 2,4-D from culture medium during one subculture of
Catharanthus roseus cells, strain C20, resulted in an increased alkaloid accumulation, without effect on growth. Alkaloid accumulation, rather than growth, seemed to be more sensitive to 2,4-D. 2,4-D inhibited alkaloid accumulation essentially during growth phase, but its inhibitory effect during this period was partially reversible. As this reversibility was underlined only during the stationary phase, this suggested that this action could be situated upstream in a terpenoid non-specific pathway. 2,4-D feeding showed that inhibition is weaker and weaker as the alkaloid accumulation period proceeds. Auxin action during this period could take place downstream in specific alkaloid pathways. The lower alkaloid accumulation obtained after loganic acid feeding compared to that obtained with secologanin and loganin could indicate that loganic acid methylation should be one of the 2,4-D target(s).</description><identifier>ISSN: 0300-9084</identifier><identifier>EISSN: 1638-6183</identifier><identifier>DOI: 10.1016/0300-9084(94)90117-1</identifier><identifier>PMID: 7849107</identifier><language>eng</language><publisher>France: Elsevier Masson SAS</publisher><subject>2,4-D ; 2,4-Dichlorophenoxyacetic Acid - metabolism ; ALCALOIDE ; ALCALOIDES ; alkaloid terpenoid precursor ; ALKALOIDS ; BIOCHEMICAL PATHWAYS ; CATHARANTHUS ROSEUS ; CELL CULTURE ; cell suspension ; Cells, Cultured ; CULTIVO DE CELULAS ; CULTURE DE CELLULE ; Glucosides - pharmacology ; indole alkaloid ; INHIBICION ; INHIBITION ; Iridoid Glucosides ; Iridoids ; PLANT GROWTH SUBSTANCES ; Plants, Medicinal - cytology ; Plants, Medicinal - metabolism ; Pyrans - pharmacology ; Secologanin Tryptamine Alkaloids ; SUBSTANCE DE CROISSANCE VEGETALE ; SUSTANCIAS DE CRECIMIENTO VEGETAL ; VIA BIOQUIMICA DEL METABOLISMO ; Vinca Alkaloids - metabolism ; VOIE BIOCHIMIQUE DU METABOLISME ; Yohimbine - analogs & derivatives ; Yohimbine - metabolism</subject><ispartof>Biochimie, 1994, Vol.76 (5), p.410-416</ispartof><rights>1994</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c376t-eaa7744358c40513e425e6d5b0afd325a677f359bb0e2114fc27fa97f5e327723</citedby><cites>FETCH-LOGICAL-c376t-eaa7744358c40513e425e6d5b0afd325a677f359bb0e2114fc27fa97f5e327723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0300-9084(94)90117-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,4010,27904,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7849107$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arvy, M.P.</creatorcontrib><creatorcontrib>Imbault, N.</creatorcontrib><creatorcontrib>Naudascher, F.</creatorcontrib><creatorcontrib>Thiersault, M.</creatorcontrib><creatorcontrib>Doireau, P.</creatorcontrib><title>2,4-D and alkaloid accumulation in periwinkle cell suspensions</title><title>Biochimie</title><addtitle>Biochimie</addtitle><description>Omission of 2,4-D from culture medium during one subculture of
Catharanthus roseus cells, strain C20, resulted in an increased alkaloid accumulation, without effect on growth. Alkaloid accumulation, rather than growth, seemed to be more sensitive to 2,4-D. 2,4-D inhibited alkaloid accumulation essentially during growth phase, but its inhibitory effect during this period was partially reversible. As this reversibility was underlined only during the stationary phase, this suggested that this action could be situated upstream in a terpenoid non-specific pathway. 2,4-D feeding showed that inhibition is weaker and weaker as the alkaloid accumulation period proceeds. Auxin action during this period could take place downstream in specific alkaloid pathways. The lower alkaloid accumulation obtained after loganic acid feeding compared to that obtained with secologanin and loganin could indicate that loganic acid methylation should be one of the 2,4-D target(s).</description><subject>2,4-D</subject><subject>2,4-Dichlorophenoxyacetic Acid - metabolism</subject><subject>ALCALOIDE</subject><subject>ALCALOIDES</subject><subject>alkaloid terpenoid precursor</subject><subject>ALKALOIDS</subject><subject>BIOCHEMICAL PATHWAYS</subject><subject>CATHARANTHUS ROSEUS</subject><subject>CELL CULTURE</subject><subject>cell suspension</subject><subject>Cells, Cultured</subject><subject>CULTIVO DE CELULAS</subject><subject>CULTURE DE CELLULE</subject><subject>Glucosides - pharmacology</subject><subject>indole alkaloid</subject><subject>INHIBICION</subject><subject>INHIBITION</subject><subject>Iridoid Glucosides</subject><subject>Iridoids</subject><subject>PLANT GROWTH SUBSTANCES</subject><subject>Plants, Medicinal - cytology</subject><subject>Plants, Medicinal - metabolism</subject><subject>Pyrans - pharmacology</subject><subject>Secologanin Tryptamine Alkaloids</subject><subject>SUBSTANCE DE CROISSANCE VEGETALE</subject><subject>SUSTANCIAS DE CRECIMIENTO VEGETAL</subject><subject>VIA BIOQUIMICA DEL METABOLISMO</subject><subject>Vinca Alkaloids - metabolism</subject><subject>VOIE BIOCHIMIQUE DU METABOLISME</subject><subject>Yohimbine - analogs & derivatives</subject><subject>Yohimbine - metabolism</subject><issn>0300-9084</issn><issn>1638-6183</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUhoMoc07_gCj0ShSsJk3SNDcDmU6FgSB6HdL0VOL6MZNW8d-b0rFL4UAOPO85JzwInRF8QzBJbzHFOJY4Y5eSXUlMiIjJHpqSlGZxSjK6j6a7yCE68v4TY8xxIidoIjImCRZTNE-uWXwf6aaIdLXWVWtDY0xf95XubNtEtok24OyPbdYVRAaqKvK930DjA_XH6KDUlYeT7TtD78uHt8VTvHp5fF7crWJDRdrFoLUQjFGeGYY5ocASDmnBc6zLgiZcp0KUlMs8x5AQwkqTiFJLUXKgiRAJnaGLce_GtV89-E7V1g-f0Q20vVcihFImhyAbg8a13jso1cbZWrtfRbAatKnBiRqcKBlq0KZIGDvf7u_zGord0NZT4KcjL3Wr9IezXi1fZZDJJA9wPkIIBr4tOOWNhcZAYR2YThWt_f_6H3SLgnQ</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>Arvy, M.P.</creator><creator>Imbault, N.</creator><creator>Naudascher, F.</creator><creator>Thiersault, M.</creator><creator>Doireau, P.</creator><general>Elsevier Masson SAS</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>2,4-D and alkaloid accumulation in periwinkle cell suspensions</title><author>Arvy, M.P. ; Imbault, N. ; Naudascher, F. ; Thiersault, M. ; Doireau, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c376t-eaa7744358c40513e425e6d5b0afd325a677f359bb0e2114fc27fa97f5e327723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>2,4-D</topic><topic>2,4-Dichlorophenoxyacetic Acid - metabolism</topic><topic>ALCALOIDE</topic><topic>ALCALOIDES</topic><topic>alkaloid terpenoid precursor</topic><topic>ALKALOIDS</topic><topic>BIOCHEMICAL PATHWAYS</topic><topic>CATHARANTHUS ROSEUS</topic><topic>CELL CULTURE</topic><topic>cell suspension</topic><topic>Cells, Cultured</topic><topic>CULTIVO DE CELULAS</topic><topic>CULTURE DE CELLULE</topic><topic>Glucosides - pharmacology</topic><topic>indole alkaloid</topic><topic>INHIBICION</topic><topic>INHIBITION</topic><topic>Iridoid Glucosides</topic><topic>Iridoids</topic><topic>PLANT GROWTH SUBSTANCES</topic><topic>Plants, Medicinal - cytology</topic><topic>Plants, Medicinal - metabolism</topic><topic>Pyrans - pharmacology</topic><topic>Secologanin Tryptamine Alkaloids</topic><topic>SUBSTANCE DE CROISSANCE VEGETALE</topic><topic>SUSTANCIAS DE CRECIMIENTO VEGETAL</topic><topic>VIA BIOQUIMICA DEL METABOLISMO</topic><topic>Vinca Alkaloids - metabolism</topic><topic>VOIE BIOCHIMIQUE DU METABOLISME</topic><topic>Yohimbine - analogs & derivatives</topic><topic>Yohimbine - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arvy, M.P.</creatorcontrib><creatorcontrib>Imbault, N.</creatorcontrib><creatorcontrib>Naudascher, F.</creatorcontrib><creatorcontrib>Thiersault, M.</creatorcontrib><creatorcontrib>Doireau, P.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biochimie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arvy, M.P.</au><au>Imbault, N.</au><au>Naudascher, F.</au><au>Thiersault, M.</au><au>Doireau, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>2,4-D and alkaloid accumulation in periwinkle cell suspensions</atitle><jtitle>Biochimie</jtitle><addtitle>Biochimie</addtitle><date>1994</date><risdate>1994</risdate><volume>76</volume><issue>5</issue><spage>410</spage><epage>416</epage><pages>410-416</pages><issn>0300-9084</issn><eissn>1638-6183</eissn><abstract>Omission of 2,4-D from culture medium during one subculture of
Catharanthus roseus cells, strain C20, resulted in an increased alkaloid accumulation, without effect on growth. Alkaloid accumulation, rather than growth, seemed to be more sensitive to 2,4-D. 2,4-D inhibited alkaloid accumulation essentially during growth phase, but its inhibitory effect during this period was partially reversible. As this reversibility was underlined only during the stationary phase, this suggested that this action could be situated upstream in a terpenoid non-specific pathway. 2,4-D feeding showed that inhibition is weaker and weaker as the alkaloid accumulation period proceeds. Auxin action during this period could take place downstream in specific alkaloid pathways. The lower alkaloid accumulation obtained after loganic acid feeding compared to that obtained with secologanin and loganin could indicate that loganic acid methylation should be one of the 2,4-D target(s).</abstract><cop>France</cop><pub>Elsevier Masson SAS</pub><pmid>7849107</pmid><doi>10.1016/0300-9084(94)90117-1</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-9084 |
| ispartof | Biochimie, 1994, Vol.76 (5), p.410-416 |
| issn | 0300-9084 1638-6183 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77726492 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | 2,4-D 2,4-Dichlorophenoxyacetic Acid - metabolism ALCALOIDE ALCALOIDES alkaloid terpenoid precursor ALKALOIDS BIOCHEMICAL PATHWAYS CATHARANTHUS ROSEUS CELL CULTURE cell suspension Cells, Cultured CULTIVO DE CELULAS CULTURE DE CELLULE Glucosides - pharmacology indole alkaloid INHIBICION INHIBITION Iridoid Glucosides Iridoids PLANT GROWTH SUBSTANCES Plants, Medicinal - cytology Plants, Medicinal - metabolism Pyrans - pharmacology Secologanin Tryptamine Alkaloids SUBSTANCE DE CROISSANCE VEGETALE SUSTANCIAS DE CRECIMIENTO VEGETAL VIA BIOQUIMICA DEL METABOLISMO Vinca Alkaloids - metabolism VOIE BIOCHIMIQUE DU METABOLISME Yohimbine - analogs & derivatives Yohimbine - metabolism |
| title | 2,4-D and alkaloid accumulation in periwinkle cell suspensions |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T16%3A04%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=2,4-D%20and%20alkaloid%20accumulation%20in%20periwinkle%20cell%20suspensions&rft.jtitle=Biochimie&rft.au=Arvy,%20M.P.&rft.date=1994&rft.volume=76&rft.issue=5&rft.spage=410&rft.epage=416&rft.pages=410-416&rft.issn=0300-9084&rft.eissn=1638-6183&rft_id=info:doi/10.1016/0300-9084(94)90117-1&rft_dat=%3Cproquest_cross%3E77726492%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77726492&rft_id=info:pmid/7849107&rft_els_id=0300908494901171&rfr_iscdi=true |