Assignment of the Human Prostaglandin-Endoperoxide Synthase 2 (PTGS2) Gene to 1q25 by Fluorescence in Situ Hybridization

A major mechanism for the regulation of prostaglandin synthesis occurs at the level of cyclooxygenase, also known as prostaglandin-endoperoxide synthase (PTGS). Two isoforms of PTGS have been identified: PTGS1, encoded by a 2.8-kb mRNA and a mitogen-inducible form, PTGS2, encoded by a 4.5-kb mRNA. W...

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Veröffentlicht in:	Genomics 1994-10, Vol.23 (3), p.718-719
Hauptverfasser:	Tay, A., Squire, J.A., Goldberg, H., Skorecki, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences BIOLOGY AND MEDICINE, BASIC STUDIES BIOSYNTHESIS Chromosome Mapping Chromosomes, Human, Pair 1 Classical genetics, quantitative genetics, hybrids DNA HYBRIDIZATION DNA Primers DNA SEQUENCING FLUORESCENCE Fundamental and applied biological sciences. Psychology GENES GENETIC MAPPING Genetics of eukaryotes. Biological and molecular evolution Hominidae - genetics Human HUMAN CHROMOSOME 1 Humans In Situ Hybridization, Fluorescence MESSENGER-RNA Molecular Sequence Data NUCLEOTIDES Phospholipases A - genetics POLYMERASE CHAIN REACTION Prostaglandin-Endoperoxide Synthases - genetics PROSTAGLANDINS
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