The mouse scurfy (sf) mutation is tightly linked to Gata1 and Tfe3 on the proximal X chromosome

In the mouse, the X-linked recessive mutation scurfy (sf) results in a rapidly fatal lymphoreticular disease that is characterized by runting, exfoliative dermatitis, lymphadenopathy, hepatosplenomegaly, thymic atrophy, and severe anemia. T cells mediate disease in the scurfy mouse, with CD4 super(+...

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Veröffentlicht in:	Mammalian genome 1994-10, Vol.5 (10), p.652-654
Hauptverfasser:	Blair, P J, Carpenter, D A, Godfrey, V L, Russell, L B, Wilkinson, J E, Rinchik, E M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosome Mapping Crosses, Genetic Disease Models, Animal Female Genes, Recessive Genetic Linkage Humans Lymphatic Diseases - genetics Male Mice Mice, Mutant Strains Muridae Mus musculus Mus spretus Mutation Wiskott-Aldrich Syndrome - genetics X Chromosome
Online-Zugang:	Volltext
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