Comparison of the positional cloning methods used to isolate the BRCA1 gene

A critical step in positional cloning is the identification of candidate genes from a large, genetically defined region. Candidate gene isolation by hybrid selection, genomic sequencing, and direct cDNA library screening identified 45 candidate gene fragments (CGFs) from a 600 kb genomic region that...

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Veröffentlicht in:	Human molecular genetics 1995-08, Vol.4 (8), p.1259-1266
Hauptverfasser:	Harshman, Keith, Bell, Russell, Rosenthal, Judith, Katcher, Harold, MlKl, Yoshio, Swenson, Jeff, Gholami, Zahra, Frye, Cheryl, Ding, Wei, Dayananth, Priya, Eddington, Ken, Norris, Franklin H., Bristow, Pamela K., Phelps, Robert, Haltier, Thomas, Stone, Steven, Shaffer, Daniel, Bayer, Steven, Hussey, Charles, Tran, Thanh, Richardson, Katherine, Dehoff, Brad, Lai, Mei, Rosteck, Paul R., Skolnick, Mark H., Shattuck-Eidens, Donna, Kamb, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences BRCA1 gene breast Breast Neoplasms - genetics Chromosome Mapping Chromosomes, Human, Pair 17 - genetics cloning Cloning, Molecular - methods DNA, Complementary - genetics Female Genome, Human Gynecology. Andrology. Obstetrics Humans Mammary gland diseases man Medical sciences methodology Molecular Sequence Data nucleotide sequence Oncogenes Tumors
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