Characterization of the Phosphatidylinositol-Glycan Membrane Anchor of Human Placental Alkaline Phosphatase

Placental alkaline phosphatase [orthophosphoric-monoester phosphohydrolase (alkaline optimum), EC 3.1.3.1] is a member of a diverse group of membrane proteins whose attachment to the lipid bilayer is mediated by a phosphatidylinositol-glycan. To investigate structural aspects of the glycolipid ancho...

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Veröffentlicht in:	Proc. Natl. Acad. Sci. U.S.A.; (United States) 1987-09, Vol.84 (17), p.6055-6059
Hauptverfasser:	Howard, Andrew D., Berger, Joel, Gerber, Louise, Familletti, Philip, Udenfriend, Sidney
Format:	Artikel
Sprache:	eng
Schlagworte:	550201 - Biochemistry- Tracer Techniques ALKALINE PHOSPHATASE Alkaline Phosphatase - metabolism AMINES AMINO ACIDS ANIMAL CELLS BASIC BIOLOGICAL SCIENCES BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Binding Sites BIOCHEMISTRY Biological and medical sciences BIOSYNTHESIS CARBOHYDRATES CARBON 14 COMPOUNDS CARBOXYLIC ACIDS CELL CONSTITUENTS Cell Line Cell lines Cell Membrane - metabolism CELL MEMBRANES Cell membranes. Ionic channels. Membrane pores Cell structures and functions CHEMISTRY CHROMATOGRAPHY DAYS LIVING RADIOISOTOPES DRUGS ELECTROPHORESIS ENZYMES ESTERASES EVEN-ODD NUCLEI Fatty acids FETAL MEMBRANES Functional groups Fundamental and applied biological sciences. Psychology GLYCOLIPIDS HeLa cells Humans HYBRIDIZATION HYDROLASES INOSITOLS ISOTOPES LABELLED COMPOUNDS LIGHT NUCLEI LIPIDS LIPOTROPIC FACTORS LIQUID COLUMN CHROMATOGRAPHY man MEMBRANES MESSENGER-RNA METHIONINE Molecular and cellular biology MONOCARBOXYLIC ACIDS MONOSACCHARIDES NUCLEI NUCLEIC ACIDS ORGANIC ACIDS ORGANIC COMPOUNDS ORGANIC SULFUR COMPOUNDS PHOSPHATASES Phosphatidylinositol Diacylglycerol-Lyase Phosphoinositide Phospholipase C Phosphoric Diester Hydrolases - metabolism PLACENTA Placenta - metabolism Proteins Radioactive decay RADIOISOTOPES RNA SACCHARIDES SEPARATION PROCESSES SOMATIC CELLS SULFUR 35 SULFUR ISOTOPES SYNTHESIS TETRADECANOIC ACID TRITIUM COMPOUNDS
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