Acute hepatic failure after open-heart surgery in children

Acute hepatic failure (AHF) combined with acute renal failure (ARF) is a well-known complication of open-heart surgery in adults. The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the opera...

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Veröffentlicht in:Pediatric cardiology 1987-01, Vol.8 (2), p.127-130
Hauptverfasser: Sivan, Y, Nutman, J, Zeevi, B, Berant, M, Levinsky, L, Schonfeld, T
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container_end_page 130
container_issue 2
container_start_page 127
container_title Pediatric cardiology
container_volume 8
creator Sivan, Y
Nutman, J
Zeevi, B
Berant, M
Levinsky, L
Schonfeld, T
description Acute hepatic failure (AHF) combined with acute renal failure (ARF) is a well-known complication of open-heart surgery in adults. The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the operation and was treated by catecholamine vasopressors. AHF set in during the postoperative course; it was manifested by impaired consciousness, hypoglycemia, hyperbilirubinemia, hyperammonemia, elevated liver enzymes and prolongation of the prothrombin time with failure of hemostasis. ARF also developed in both children. One of the patients survived the acute episode of hepatic failure. The importance of early diagnosis, routine close monitoring, and appropriate selection of vasopressors is emphasized.
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subjects Acute Disease
Acute Kidney Injury - etiology
Cardiac Surgical Procedures
Humans
Hypotension - complications
Infant, Newborn
Intraoperative Complications
Ischemia - etiology
Liver - blood supply
Liver Diseases - etiology
Postoperative Complications - etiology
title Acute hepatic failure after open-heart surgery in children
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