Acute hepatic failure after open-heart surgery in children
Acute hepatic failure (AHF) combined with acute renal failure (ARF) is a well-known complication of open-heart surgery in adults. The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the opera...
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Veröffentlicht in: | Pediatric cardiology 1987-01, Vol.8 (2), p.127-130 |
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creator | Sivan, Y Nutman, J Zeevi, B Berant, M Levinsky, L Schonfeld, T |
description | Acute hepatic failure (AHF) combined with acute renal failure (ARF) is a well-known complication of open-heart surgery in adults. The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the operation and was treated by catecholamine vasopressors. AHF set in during the postoperative course; it was manifested by impaired consciousness, hypoglycemia, hyperbilirubinemia, hyperammonemia, elevated liver enzymes and prolongation of the prothrombin time with failure of hemostasis. ARF also developed in both children. One of the patients survived the acute episode of hepatic failure. The importance of early diagnosis, routine close monitoring, and appropriate selection of vasopressors is emphasized. |
doi_str_mv | 10.1007/BF02079469 |
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The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the operation and was treated by catecholamine vasopressors. AHF set in during the postoperative course; it was manifested by impaired consciousness, hypoglycemia, hyperbilirubinemia, hyperammonemia, elevated liver enzymes and prolongation of the prothrombin time with failure of hemostasis. ARF also developed in both children. One of the patients survived the acute episode of hepatic failure. 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The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the operation and was treated by catecholamine vasopressors. AHF set in during the postoperative course; it was manifested by impaired consciousness, hypoglycemia, hyperbilirubinemia, hyperammonemia, elevated liver enzymes and prolongation of the prothrombin time with failure of hemostasis. ARF also developed in both children. One of the patients survived the acute episode of hepatic failure. The importance of early diagnosis, routine close monitoring, and appropriate selection of vasopressors is emphasized.</description><subject>Acute Disease</subject><subject>Acute Kidney Injury - etiology</subject><subject>Cardiac Surgical Procedures</subject><subject>Humans</subject><subject>Hypotension - complications</subject><subject>Infant, Newborn</subject><subject>Intraoperative Complications</subject><subject>Ischemia - etiology</subject><subject>Liver - blood supply</subject><subject>Liver Diseases - etiology</subject><subject>Postoperative Complications - etiology</subject><issn>0172-0643</issn><issn>1432-1971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDtPwzAURi0EKiWwsCN5YkAKXD_wg61UFJAqscAcOfYNDUqTYCdD_z1UjWD6lqMjfYeQSwa3DEDfPa6Ag7ZS2SMyZ1LwnFnNjskcmOY5KClOyVlKXwBgwNzPyEwobkCZOXlY-HFAusHeDbWnlaubMSJ11YCRdj22-QZdHGga4yfGHa1b6jd1EyK25-Skck3Ci2kz8rF6el--5Ou359flYp17bviQixAcA8utl-ikUUKrSiJK5GiMDwYCls54JZwJIFEIFkpU3oJFKwV4kZHrg7eP3feIaSi2dfLYNK7FbkyF1hrU_mRGbg6gj11KEauij_XWxV3BoNiHKv5D_cJXk3Ustxj-0KmM-AFvkGI-</recordid><startdate>19870101</startdate><enddate>19870101</enddate><creator>Sivan, Y</creator><creator>Nutman, J</creator><creator>Zeevi, B</creator><creator>Berant, M</creator><creator>Levinsky, L</creator><creator>Schonfeld, T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19870101</creationdate><title>Acute hepatic failure after open-heart surgery in children</title><author>Sivan, Y ; Nutman, J ; Zeevi, B ; Berant, M ; Levinsky, L ; Schonfeld, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-3dda10929c4ea486376f4ee4e2e88cd80deba8c63a8d04e331dbe6c909e9430c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Acute Disease</topic><topic>Acute Kidney Injury - etiology</topic><topic>Cardiac Surgical Procedures</topic><topic>Humans</topic><topic>Hypotension - complications</topic><topic>Infant, Newborn</topic><topic>Intraoperative Complications</topic><topic>Ischemia - etiology</topic><topic>Liver - blood supply</topic><topic>Liver Diseases - etiology</topic><topic>Postoperative Complications - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sivan, Y</creatorcontrib><creatorcontrib>Nutman, J</creatorcontrib><creatorcontrib>Zeevi, B</creatorcontrib><creatorcontrib>Berant, M</creatorcontrib><creatorcontrib>Levinsky, L</creatorcontrib><creatorcontrib>Schonfeld, T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sivan, Y</au><au>Nutman, J</au><au>Zeevi, B</au><au>Berant, M</au><au>Levinsky, L</au><au>Schonfeld, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute hepatic failure after open-heart surgery in children</atitle><jtitle>Pediatric cardiology</jtitle><addtitle>Pediatr Cardiol</addtitle><date>1987-01-01</date><risdate>1987</risdate><volume>8</volume><issue>2</issue><spage>127</spage><epage>130</epage><pages>127-130</pages><issn>0172-0643</issn><eissn>1432-1971</eissn><abstract>Acute hepatic failure (AHF) combined with acute renal failure (ARF) is a well-known complication of open-heart surgery in adults. The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the operation and was treated by catecholamine vasopressors. AHF set in during the postoperative course; it was manifested by impaired consciousness, hypoglycemia, hyperbilirubinemia, hyperammonemia, elevated liver enzymes and prolongation of the prothrombin time with failure of hemostasis. ARF also developed in both children. One of the patients survived the acute episode of hepatic failure. The importance of early diagnosis, routine close monitoring, and appropriate selection of vasopressors is emphasized.</abstract><cop>United States</cop><pmid>3628068</pmid><doi>10.1007/BF02079469</doi><tpages>4</tpages></addata></record> |
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subjects | Acute Disease Acute Kidney Injury - etiology Cardiac Surgical Procedures Humans Hypotension - complications Infant, Newborn Intraoperative Complications Ischemia - etiology Liver - blood supply Liver Diseases - etiology Postoperative Complications - etiology |
title | Acute hepatic failure after open-heart surgery in children |
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