Strand bias of ultraviolet light-induced mutations in a transcriptionally active gene in human cells

Ultraviolet (a) ‐induced repair and mutational spectra were analyzed in an inducible marker gene, the metallothionein‐l/guamine‐xanthine phosphoribosyl transferase (a) fusion gene, carried by an Epstein‐Barr virus‐derived shuttle vector episomically maintained in human cells. The repair rate of UV p...

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Veröffentlicht in:	Molecular carcinogenesis 1995-11, Vol.14 (3), p.214-225
Hauptverfasser:	Basic-Zaninovic, Tamara, Meschini, Roberta, Calcagnile, Angelo Salvatore, Palombo, Fabio, D'errico, Mariarosaria, Sanctis, Lorenzo Proietti-De, Dogliotti, Eugenia
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cell Line, Transformed DNA - genetics DNA - radiation effects DNA Mutational Analysis DNA Repair Gene Deletion Genetic Vectors Genome, Human gpt photodimers Humans Kidney - cytology Kidney - radiation effects Metallothionein - genetics Molecular Sequence Data Mutation Pentosyltransferases - genetics Pyrimidine Dimers - metabolism recombination Transcription, Genetic Transfection Ultraviolet Rays
Online-Zugang:	Volltext
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