Extensive diversity in repeat unit sequences of the cDNA encoding the polyprotein antigen/allergen from the bovine lungworm Dictyocaulus viviparus

The complete sequence of the cDNA encoding the nematode polyprotein allergen/antigen (NPA) of the bovine lungworm Dictyocaulus viviparus was obtained by immunoscreening of cDNA expression libraries and by 5′ RACE (rapid amplification of cDNA ends). The encoded polypeptide is similar in sequence to t...

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Veröffentlicht in:	Molecular and biochemical parasitology 1995-06, Vol.72 (1), p.77-88
Hauptverfasser:	Britton, Collette, Moore, Joyce, Gilleard, John S., Kennedy, Malcolm W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence amino acid sequences Animals antigens Antigens, Helminth Base Sequence Cattle cloning complementary DNA Dictyocaulus - genetics Dictyocaulus - immunology Dictyocaulus viviparus DNA, Complementary - genetics DNA, Helminth - genetics dva-1 gene Excretory-secretory antigen Fatty Acid-Binding Proteins genbank/u02568 gene expression Gene Library Guinea Pigs Helminth Proteins - genetics Helminth Proteins - immunology Helminths - genetics heterogeneity immunochemistry lungworms Molecular Sequence Data Nematode Nematode polyprotein allergen/antigen nucleotide sequences Passive Cutaneous Anaphylaxis proteinase cleavage sites proteolysis Repetitive Sequences, Nucleic Acid RNA, Helminth - genetics RNA, Messenger - genetics Sequence Alignment Sequence Homology, Amino Acid Species Specificity structural genes
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