Induction of macrophage apoptosis by Bordetella pertussis adenylate cyclase‐hemolysin

We previously demonstrated that Bordetella pertussis induced macrophage apoptosis and that adenylate cyclase‐hemoFlysin expression is required for this phenomenom. In order to determine a role for other B. pertussis factors, such as pertussis toxin or the adhesins, pertactin and filamentous hemagglu...

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Veröffentlicht in:	FEMS microbiology letters 1995-12, Vol.134 (1), p.27-32
Hauptverfasser:	Khelef, Nadia, Guiso, Nicole
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate Cyclase Toxin Adenylate cyclase‐hemolysin Adenylyl Cyclases - metabolism Adhesins, Bacterial - pharmacology Animals Apoptosis Bacterial Outer Membrane Proteins - pharmacology Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacterial Proteins - pharmacology Bacteriology Biological and medical sciences Bordetella pertussis Bordetella pertussis - chemistry DNA - metabolism Fundamental and applied biological sciences. Psychology Hemagglutinins - pharmacology Hemolysin Proteins - pharmacology Macrophage apoptosis Macrophages - cytology Mice Microbiology Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Pertussis Toxin Protein Precursors - genetics Protein Precursors - metabolism Protein Precursors - pharmacology Recombinant Proteins - pharmacology Virulence Factors, Bordetella - pharmacology
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