Expression of interleukin 1α, interleukin 1β and interleukin 1 receptor antagonist mRNA in mouse brain: regulation by bacterial lipopolysaccharide (LPS) treatment

Lipopolysaccharide (LPS) stimulation is known to induce interleukin-1 (IL-1) mRNA expression in various immune cell types. Since IL-1 synthesis has been suggested to occur locally in brain tissue, we investigated the expression of IL-1 (α and β) and IL-1 receptor antagonist (IL-1ra) mRNAs in various...

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Veröffentlicht in:	Brain research. Molecular brain research. 1995-07, Vol.31 (1), p.122-130
Hauptverfasser:	Gabellec, Marie-Madeleine, Griffais, Rémi, Fillion, Gilles, Haour, France
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biochemistry and metabolism Biological and medical sciences Brain Brain - drug effects Brain - metabolism Central nervous system Fundamental and applied biological sciences. Psychology Injections, Intraperitoneal Interleukin 1 Receptor Antagonist Protein Interleukin-1 Interleukin-1 - genetics Interleukin-1 receptor antagonist Kinetics Lipopolysaccharide Lipopolysaccharides - pharmacology Male Mice Mice, Inbred C3H Molecular Sequence Data Recombinant Proteins - genetics RNA, Messenger - biosynthesis Sialoglycoproteins - genetics Spleen - drug effects Spleen - metabolism Stimulation, Chemical Vertebrates: nervous system and sense organs
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