Antihypertensive effects of repeated oral administration of cilnidipine, a novel calcium antagonist, in 2K1C renal hypertensive dogs

Antihypertensive effects of repeated oral administration of cilnidipine in 2K1C renal hypertensive dogs were compared with those of nicardipine. On the first day, oral administration of cilnidipine (3 mg/kg) or nicardipine (3 mg/kg) markedly lowered both systolic and diastolic blood pressure 1 hr af...

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Veröffentlicht in:	Nihon yakurigaku zasshi 1995, Vol.106 (4), p.279-287
Hauptverfasser:	Takahara, A, Uchida, H, Konda, T, Dohmoto, H, Yoshimoto, R, Komori, M, Morioka, T, Ono, I, Takata, Y, Kato, H
Format:	Artikel
Sprache:	jpn
Schlagworte:	Administration, Oral Animals Antihypertensive Agents - administration & dosage Antihypertensive Agents - pharmacokinetics Calcium Channel Blockers - administration & dosage Calcium Channel Blockers - pharmacokinetics Dihydropyridines - administration & dosage Dihydropyridines - pharmacokinetics Dogs Hypertension, Renal - drug therapy Male Renin - blood
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