"Cercariform" cells: A clue to the cytodiagnosis of transitional cell origin of metastatic neoplasms?

The “cercariform” cell is described as a distinct cytomorphologic clue that may be helpful in the diagnosis of metastatic transitional cell neoplasms, particularly low grade. This cell has a nucleated globular body and a cytoplasmic process with a nontapering, flattened, bulbous or fishtail‐like end...

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Veröffentlicht in:Diagnostic cytopathology 1995-07, Vol.13 (1), p.15-21
Hauptverfasser: Powers, Celeste N., Elbadawi, Ahmad
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container_title Diagnostic cytopathology
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creator Powers, Celeste N.
Elbadawi, Ahmad
description The “cercariform” cell is described as a distinct cytomorphologic clue that may be helpful in the diagnosis of metastatic transitional cell neoplasms, particularly low grade. This cell has a nucleated globular body and a cytoplasmic process with a nontapering, flattened, bulbous or fishtail‐like end. The cercariform cell corresponds to intermediate cells in histologic and ultrastructural preparations of normal urothelium. The cercariform appearance is the result of pseudostratification of both normal and low‐grade neoplastic urothelium. The unique features of cercariform cells make them readily distinguishable from neoplastic squamous cells as well as spindle cells of mesenchymal origin. © 1995 Wiley‐Liss, Inc.
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Urinary tract diseases ; Transitional cell neoplasm ; Tumors of the urinary system ; Urinary Bladder Neoplasms - pathology ; Urinary Bladder Neoplasms - ultrastructure ; Urinary Bladder Neoplasms - urine ; Urinary tract. 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Cytopathol</addtitle><description>The “cercariform” cell is described as a distinct cytomorphologic clue that may be helpful in the diagnosis of metastatic transitional cell neoplasms, particularly low grade. This cell has a nucleated globular body and a cytoplasmic process with a nontapering, flattened, bulbous or fishtail‐like end. The cercariform cell corresponds to intermediate cells in histologic and ultrastructural preparations of normal urothelium. The cercariform appearance is the result of pseudostratification of both normal and low‐grade neoplastic urothelium. The unique features of cercariform cells make them readily distinguishable from neoplastic squamous cells as well as spindle cells of mesenchymal origin. © 1995 Wiley‐Liss, Inc.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Transitional Cell - pathology</subject><subject>Carcinoma, Transitional Cell - secondary</subject><subject>Carcinoma, Transitional Cell - ultrastructure</subject><subject>Cercariform cell</subject><subject>Cytodiagnosis</subject><subject>Diagnosis, Differential</subject><subject>Epithelium - pathology</subject><subject>Epithelium - ultrastructure</subject><subject>Female</subject><subject>Humans</subject><subject>Intermediate cell</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Transitional cell neoplasm</subject><subject>Tumors of the urinary system</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Urinary Bladder Neoplasms - ultrastructure</subject><subject>Urinary Bladder Neoplasms - urine</subject><subject>Urinary tract. 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subjects Adult
Aged
Aged, 80 and over
Biological and medical sciences
Carcinoma, Transitional Cell - pathology
Carcinoma, Transitional Cell - secondary
Carcinoma, Transitional Cell - ultrastructure
Cercariform cell
Cytodiagnosis
Diagnosis, Differential
Epithelium - pathology
Epithelium - ultrastructure
Female
Humans
Intermediate cell
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Transitional cell neoplasm
Tumors of the urinary system
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - ultrastructure
Urinary Bladder Neoplasms - urine
Urinary tract. Prostate gland
Urothelium
title "Cercariform" cells: A clue to the cytodiagnosis of transitional cell origin of metastatic neoplasms?
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