Implantation of fetal preoptic area into the lateral ventricle of adult hypogonadal mutant mice: The pattern of gonadotropin-releasing hormone axonal outgrowth into the host brain

Transplantation of fetal preoptic area tissue containing gonadotropin-releasing hormone neurons into the third ventricle of male hypogonadal mice resulted in an elevation of pituitary gonadotropin levels and correction of hypogonadism. This reversal of the neuroendocrine deficit was correlated with...

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