Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis

The autoregulation of dopamine release and metabolism by intrastriatal grafts of mesencephalic dopamine neurons was examined in vivo using an intracerebral dialysis technique. Dopamine-rich cell suspension grafts were implanted into the head of the caudate putamen in rats with complete unilateral 6-...

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Veröffentlicht in:	Neuroscience 1987-07, Vol.22 (1), p.169-178
Hauptverfasser:	Strecker, R.E., Sharp, T., Brundin, P., Zetterström, T., Ungerstedt, U., Björklund, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apomorphine - pharmacology Biological and medical sciences Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Corpus Striatum - physiology Dopamine - metabolism Female Fundamental and applied biological sciences. Psychology Microscopy, Fluorescence Motor Activity - physiology Nerve Regeneration - drug effects Neural Pathways - physiology Nomifensine - pharmacology Perfusion Rats Rats, Inbred Strains Receptors, Dopamine - physiology Stereotyped Behavior - physiology Substantia Nigra - physiology Substantia Nigra - transplantation Synaptic Transmission - drug effects Vertebrates: nervous system and sense organs
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