Carrier Frequency of the IVS4 + 4 A → T Mutation of the Fanconi Anemia Gene FAC in the Ashkenazi Jewish Population

Fanconi anemia (FA) is a genetically and phenotypically heterogeneous autosomal recessive disorder defined by a cellular hypersensitivity to DNA cross-linking agents. One of the FA genes, FAC, has been cloned and the genomic structure of the coding region has been characterized. We have developed am...

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