Identification of the pore forming element of Semliki Forest virus spikes

Pore formation at mildly acidic pH by SFV spike proteins was investigated using isolated and modified virions. Modification of the virions was performed by limited proteolysis in presence of octylglucoside and resulted in the formation of E1 particles and spikeless particles, respectively. Pore form...

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Veröffentlicht in:	FEBS letters 1995-11, Vol.375 (1), p.134-136
Hauptverfasser:	Spyr, Christian A., Käsermann, Fabian, Kempf, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	Aedes Animals Chlorides - pharmacology Clone Cells E1 protein Electrophoresis, Polyacrylamide Gel Glucosides Hydrogen-Ion Concentration Kinetics Pore formation Propidium - metabolism Semliki Forest virus Semliki forest virus - physiology Viral Envelope Proteins - analysis Viral Envelope Proteins - antagonists & inhibitors Viral Envelope Proteins - metabolism Zinc Compounds - pharmacology
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