Hypoxic Ischaemic Encephalopathy: Early Magnetic Resonance Imaging Findings and Their Evolution
Abstract Eighteen term infants with hypoxic ischaemic encephalopathy (HIE) were studied with serial magnetic resonance imaging of the brain for up to two months following birth. Important early findings included brain swelling, cortical highlighting, diffuse loss of grey/white differentiation and lo...
Gespeichert in:
| Veröffentlicht in: | Neuropediatrics 1995-08, Vol.26 (4), p.183-191 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 191 |
|---|---|
| container_issue | 4 |
| container_start_page | 183 |
| container_title | Neuropediatrics |
| container_volume | 26 |
| creator | Rutherford, M. A. Pennock, J. M. Schwieso, J. E. Cowan, F. M. Dubowitz, L. M. |
| description | Abstract
Eighteen term infants with hypoxic ischaemic encephalopathy (HIE) were studied with serial magnetic resonance imaging of the brain for up to two months following birth. Important early findings included brain swelling, cortical highlighting, diffuse loss of grey/white differentiation and loss of signal in the posterior limb of the internal capsule (PLIC). These signs were easier to identify on T
1
-weighted spin echo or inversion recovery sequences than on T
2-
weighted spin echo sequences. Brain swelling was only seen in the first seven days and was present in all grades of HIE. All other signs persisted and were associated with the subsequent development of major structural changes in the brain. The exact pattern of injury was best identified after the first week of life once the signs of brain swelling had cleared. |
| doi_str_mv | 10.1055/s-2007-979751 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77693712</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>77693712</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2691-1c2fa47f5b28f9013fca6f860b95d1a72a9c4d095094241281b8555a9f4cccfb3</originalsourceid><addsrcrecordid>eNp1kE1r3DAURUVpSadpll0WvChd1a0k68PqLoRJM5AQKClkJ55laaxgS65kl86_r8IM2XV1H9zDfXAQ-kDwV4I5_5ZrirGslVSSk1doQ1ijatIq9RptMJGsbjB7fIve5fyEMWEKizN01nLGFBcbpG8Oc_zrTbXLZgA7lWsbjJ0HGOMMy3D4Xm0hjYfqDvbBLqX-aXMMUJhqN8Heh3117UNfMlcQ-uphsD5V2z9xXBcfw3v0xsGY7cUpz9Gv6-3D1U19e_9jd3V5WxsqFKmJoQ6YdLyjrVOYNM6AcK3AneI9AUlBGdZjxbFilBHakq7lnINyzBjjuuYcfT7uzin-Xm1e9OSzseMIwcY1aymFaiShBayPoEkx52SdnpOfIB00wfpZqM76Wag-Ci38x9Pw2k22f6FPBkv_6dRDNjC6VNT4_II1gglBm4J9OWLL4O1k9VNcUyhC_vP1H-oCi2g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77693712</pqid></control><display><type>article</type><title>Hypoxic Ischaemic Encephalopathy: Early Magnetic Resonance Imaging Findings and Their Evolution</title><source>MEDLINE</source><source>Thieme Connect Journals</source><creator>Rutherford, M. A. ; Pennock, J. M. ; Schwieso, J. E. ; Cowan, F. M. ; Dubowitz, L. M.</creator><creatorcontrib>Rutherford, M. A. ; Pennock, J. M. ; Schwieso, J. E. ; Cowan, F. M. ; Dubowitz, L. M.</creatorcontrib><description>Abstract
Eighteen term infants with hypoxic ischaemic encephalopathy (HIE) were studied with serial magnetic resonance imaging of the brain for up to two months following birth. Important early findings included brain swelling, cortical highlighting, diffuse loss of grey/white differentiation and loss of signal in the posterior limb of the internal capsule (PLIC). These signs were easier to identify on T
1
-weighted spin echo or inversion recovery sequences than on T
2-
weighted spin echo sequences. Brain swelling was only seen in the first seven days and was present in all grades of HIE. All other signs persisted and were associated with the subsequent development of major structural changes in the brain. The exact pattern of injury was best identified after the first week of life once the signs of brain swelling had cleared.</description><identifier>ISSN: 0174-304X</identifier><identifier>EISSN: 1439-1899</identifier><identifier>DOI: 10.1055/s-2007-979751</identifier><identifier>PMID: 8544956</identifier><identifier>CODEN: NRPDDB</identifier><language>eng</language><publisher>Stuttgart: Thieme</publisher><subject>Asphyxia Neonatorum - etiology ; Asphyxia Neonatorum - physiopathology ; Basal Ganglia - physiopathology ; Biological and medical sciences ; Brain Ischemia - complications ; Brain Ischemia - physiopathology ; Cerebral Ventricles - abnormalities ; Frontal Lobe - physiopathology ; Hippocampus - physiopathology ; Humans ; Hypoxia - complications ; Hypoxia - physiopathology ; Infant, Newborn ; Magnetic Resonance Imaging ; Medical sciences ; Neurology ; Occipital Lobe - physiopathology ; Original articles ; Severity of Illness Index ; Thalamus - physiopathology ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Neuropediatrics, 1995-08, Vol.26 (4), p.183-191</ispartof><rights>Hippokrates Verlag GmbH Stuttgart</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2691-1c2fa47f5b28f9013fca6f860b95d1a72a9c4d095094241281b8555a9f4cccfb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-979751.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,776,780,3004,3005,27901,27902,54534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3646623$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8544956$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rutherford, M. A.</creatorcontrib><creatorcontrib>Pennock, J. M.</creatorcontrib><creatorcontrib>Schwieso, J. E.</creatorcontrib><creatorcontrib>Cowan, F. M.</creatorcontrib><creatorcontrib>Dubowitz, L. M.</creatorcontrib><title>Hypoxic Ischaemic Encephalopathy: Early Magnetic Resonance Imaging Findings and Their Evolution</title><title>Neuropediatrics</title><addtitle>Neuropediatrics</addtitle><description>Abstract
Eighteen term infants with hypoxic ischaemic encephalopathy (HIE) were studied with serial magnetic resonance imaging of the brain for up to two months following birth. Important early findings included brain swelling, cortical highlighting, diffuse loss of grey/white differentiation and loss of signal in the posterior limb of the internal capsule (PLIC). These signs were easier to identify on T
1
-weighted spin echo or inversion recovery sequences than on T
2-
weighted spin echo sequences. Brain swelling was only seen in the first seven days and was present in all grades of HIE. All other signs persisted and were associated with the subsequent development of major structural changes in the brain. The exact pattern of injury was best identified after the first week of life once the signs of brain swelling had cleared.</description><subject>Asphyxia Neonatorum - etiology</subject><subject>Asphyxia Neonatorum - physiopathology</subject><subject>Basal Ganglia - physiopathology</subject><subject>Biological and medical sciences</subject><subject>Brain Ischemia - complications</subject><subject>Brain Ischemia - physiopathology</subject><subject>Cerebral Ventricles - abnormalities</subject><subject>Frontal Lobe - physiopathology</subject><subject>Hippocampus - physiopathology</subject><subject>Humans</subject><subject>Hypoxia - complications</subject><subject>Hypoxia - physiopathology</subject><subject>Infant, Newborn</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Neurology</subject><subject>Occipital Lobe - physiopathology</subject><subject>Original articles</subject><subject>Severity of Illness Index</subject><subject>Thalamus - physiopathology</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0174-304X</issn><issn>1439-1899</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1r3DAURUVpSadpll0WvChd1a0k68PqLoRJM5AQKClkJ55laaxgS65kl86_r8IM2XV1H9zDfXAQ-kDwV4I5_5ZrirGslVSSk1doQ1ijatIq9RptMJGsbjB7fIve5fyEMWEKizN01nLGFBcbpG8Oc_zrTbXLZgA7lWsbjJ0HGOMMy3D4Xm0hjYfqDvbBLqX-aXMMUJhqN8Heh3117UNfMlcQ-uphsD5V2z9xXBcfw3v0xsGY7cUpz9Gv6-3D1U19e_9jd3V5WxsqFKmJoQ6YdLyjrVOYNM6AcK3AneI9AUlBGdZjxbFilBHakq7lnINyzBjjuuYcfT7uzin-Xm1e9OSzseMIwcY1aymFaiShBayPoEkx52SdnpOfIB00wfpZqM76Wag-Ci38x9Pw2k22f6FPBkv_6dRDNjC6VNT4_II1gglBm4J9OWLL4O1k9VNcUyhC_vP1H-oCi2g</recordid><startdate>199508</startdate><enddate>199508</enddate><creator>Rutherford, M. A.</creator><creator>Pennock, J. M.</creator><creator>Schwieso, J. E.</creator><creator>Cowan, F. M.</creator><creator>Dubowitz, L. M.</creator><general>Thieme</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199508</creationdate><title>Hypoxic Ischaemic Encephalopathy: Early Magnetic Resonance Imaging Findings and Their Evolution</title><author>Rutherford, M. A. ; Pennock, J. M. ; Schwieso, J. E. ; Cowan, F. M. ; Dubowitz, L. M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2691-1c2fa47f5b28f9013fca6f860b95d1a72a9c4d095094241281b8555a9f4cccfb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Asphyxia Neonatorum - etiology</topic><topic>Asphyxia Neonatorum - physiopathology</topic><topic>Basal Ganglia - physiopathology</topic><topic>Biological and medical sciences</topic><topic>Brain Ischemia - complications</topic><topic>Brain Ischemia - physiopathology</topic><topic>Cerebral Ventricles - abnormalities</topic><topic>Frontal Lobe - physiopathology</topic><topic>Hippocampus - physiopathology</topic><topic>Humans</topic><topic>Hypoxia - complications</topic><topic>Hypoxia - physiopathology</topic><topic>Infant, Newborn</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Neurology</topic><topic>Occipital Lobe - physiopathology</topic><topic>Original articles</topic><topic>Severity of Illness Index</topic><topic>Thalamus - physiopathology</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rutherford, M. A.</creatorcontrib><creatorcontrib>Pennock, J. M.</creatorcontrib><creatorcontrib>Schwieso, J. E.</creatorcontrib><creatorcontrib>Cowan, F. M.</creatorcontrib><creatorcontrib>Dubowitz, L. M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuropediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rutherford, M. A.</au><au>Pennock, J. M.</au><au>Schwieso, J. E.</au><au>Cowan, F. M.</au><au>Dubowitz, L. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypoxic Ischaemic Encephalopathy: Early Magnetic Resonance Imaging Findings and Their Evolution</atitle><jtitle>Neuropediatrics</jtitle><addtitle>Neuropediatrics</addtitle><date>1995-08</date><risdate>1995</risdate><volume>26</volume><issue>4</issue><spage>183</spage><epage>191</epage><pages>183-191</pages><issn>0174-304X</issn><eissn>1439-1899</eissn><coden>NRPDDB</coden><abstract>Abstract
Eighteen term infants with hypoxic ischaemic encephalopathy (HIE) were studied with serial magnetic resonance imaging of the brain for up to two months following birth. Important early findings included brain swelling, cortical highlighting, diffuse loss of grey/white differentiation and loss of signal in the posterior limb of the internal capsule (PLIC). These signs were easier to identify on T
1
-weighted spin echo or inversion recovery sequences than on T
2-
weighted spin echo sequences. Brain swelling was only seen in the first seven days and was present in all grades of HIE. All other signs persisted and were associated with the subsequent development of major structural changes in the brain. The exact pattern of injury was best identified after the first week of life once the signs of brain swelling had cleared.</abstract><cop>Stuttgart</cop><pub>Thieme</pub><pmid>8544956</pmid><doi>10.1055/s-2007-979751</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0174-304X |
| ispartof | Neuropediatrics, 1995-08, Vol.26 (4), p.183-191 |
| issn | 0174-304X 1439-1899 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77693712 |
| source | MEDLINE; Thieme Connect Journals |
| subjects | Asphyxia Neonatorum - etiology Asphyxia Neonatorum - physiopathology Basal Ganglia - physiopathology Biological and medical sciences Brain Ischemia - complications Brain Ischemia - physiopathology Cerebral Ventricles - abnormalities Frontal Lobe - physiopathology Hippocampus - physiopathology Humans Hypoxia - complications Hypoxia - physiopathology Infant, Newborn Magnetic Resonance Imaging Medical sciences Neurology Occipital Lobe - physiopathology Original articles Severity of Illness Index Thalamus - physiopathology Vascular diseases and vascular malformations of the nervous system |
| title | Hypoxic Ischaemic Encephalopathy: Early Magnetic Resonance Imaging Findings and Their Evolution |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T06%3A39%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hypoxic%20Ischaemic%20Encephalopathy:%20Early%20Magnetic%20Resonance%20Imaging%20Findings%20and%20Their%20Evolution&rft.jtitle=Neuropediatrics&rft.au=Rutherford,%20M.%20A.&rft.date=1995-08&rft.volume=26&rft.issue=4&rft.spage=183&rft.epage=191&rft.pages=183-191&rft.issn=0174-304X&rft.eissn=1439-1899&rft.coden=NRPDDB&rft_id=info:doi/10.1055/s-2007-979751&rft_dat=%3Cproquest_cross%3E77693712%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77693712&rft_id=info:pmid/8544956&rfr_iscdi=true |