Intentional delivery versus expectant management with preterm ruptured membranes at 30–34 weeks' gestation
To determine maternal and neonatal outcomes in pregnancies complicated by preterm rupture of membranes (PROM) at 30–34 weeks' gestation. A randomized controlled trial was conducted to study the benefits of expectant management in women hospitalized for PROM at 30–34 weeks' gestation. Durin...
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| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1995-12, Vol.86 (6), p.875-879 |
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| container_title | Obstetrics and gynecology (New York. 1953) |
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| creator | Cox, Susan M. Leveno, Kenneth J. |
| description | To determine maternal and neonatal outcomes in pregnancies complicated by preterm rupture of membranes (PROM) at 30–34 weeks' gestation.
A randomized controlled trial was conducted to study the benefits of expectant management in women hospitalized for PROM at 30–34 weeks' gestation. During this investigation, no tocolytics, corticosteroids, or prophylactic antibiotics were used.
Sixty-eight women with PROM were managed expectantly and 61 were delivered intentionally. The mean gestational age at study entry was 31.7 weeks in both the expectant management and intentional delivery groups (
P > .05). The mean gestational ages at delivery were similar (32.0 and 31.7 weeks, respectively). Other indices of pregnancy outcome (ie, birth weight, intraventricular hemorrhage, necrotizing enterocolitis, sepsis, respiratory distress syndrome, and perinatal death) were not significantly improved by expectant management. However, there was a significant increase in the incidence of chorioamnionitis and antepartum hospitalization in the women managed expectantly.
There were no clinically significant neonatal advantages to expectant management of ruptured membranes at 30–34 weeks. Antepartum hospitalization was decreased by 2.5 days in those women randomized to intentional delivery. |
| doi_str_mv | 10.1016/0029-7844(95)00303-9 |
| format | Article |
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A randomized controlled trial was conducted to study the benefits of expectant management in women hospitalized for PROM at 30–34 weeks' gestation. During this investigation, no tocolytics, corticosteroids, or prophylactic antibiotics were used.
Sixty-eight women with PROM were managed expectantly and 61 were delivered intentionally. The mean gestational age at study entry was 31.7 weeks in both the expectant management and intentional delivery groups (
P > .05). The mean gestational ages at delivery were similar (32.0 and 31.7 weeks, respectively). Other indices of pregnancy outcome (ie, birth weight, intraventricular hemorrhage, necrotizing enterocolitis, sepsis, respiratory distress syndrome, and perinatal death) were not significantly improved by expectant management. However, there was a significant increase in the incidence of chorioamnionitis and antepartum hospitalization in the women managed expectantly.
There were no clinically significant neonatal advantages to expectant management of ruptured membranes at 30–34 weeks. Antepartum hospitalization was decreased by 2.5 days in those women randomized to intentional delivery.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1016/0029-7844(95)00303-9</identifier><identifier>PMID: 7501331</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Delivery, Obstetric - methods ; Diseases of mother, fetus and pregnancy ; Female ; Fetal Membranes, Premature Rupture ; Gynecology. Andrology. Obstetrics ; Humans ; Medical sciences ; Pregnancy ; Pregnancy Outcome ; Pregnancy Trimester, Third ; Pregnancy. Fetus. Placenta</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1995-12, Vol.86 (6), p.875-879</ispartof><rights>1995 The American College of Obstetricians and Gynecologists</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-9ea1290eb00dab2b343e8ddf44b1c3f0bd0a2352ba30b0bf05cc313fc40f53d03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2911113$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7501331$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cox, Susan M.</creatorcontrib><creatorcontrib>Leveno, Kenneth J.</creatorcontrib><title>Intentional delivery versus expectant management with preterm ruptured membranes at 30–34 weeks' gestation</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>To determine maternal and neonatal outcomes in pregnancies complicated by preterm rupture of membranes (PROM) at 30–34 weeks' gestation.
A randomized controlled trial was conducted to study the benefits of expectant management in women hospitalized for PROM at 30–34 weeks' gestation. During this investigation, no tocolytics, corticosteroids, or prophylactic antibiotics were used.
Sixty-eight women with PROM were managed expectantly and 61 were delivered intentionally. The mean gestational age at study entry was 31.7 weeks in both the expectant management and intentional delivery groups (
P > .05). The mean gestational ages at delivery were similar (32.0 and 31.7 weeks, respectively). Other indices of pregnancy outcome (ie, birth weight, intraventricular hemorrhage, necrotizing enterocolitis, sepsis, respiratory distress syndrome, and perinatal death) were not significantly improved by expectant management. However, there was a significant increase in the incidence of chorioamnionitis and antepartum hospitalization in the women managed expectantly.
There were no clinically significant neonatal advantages to expectant management of ruptured membranes at 30–34 weeks. Antepartum hospitalization was decreased by 2.5 days in those women randomized to intentional delivery.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Delivery, Obstetric - methods</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Fetal Membranes, Premature Rupture</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Pregnancy Trimester, Third</subject><subject>Pregnancy. Fetus. Placenta</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtuFDEQhi0ECpPADUDyAvFYNJS73OnxJhKKQogUKRuQ2Fl-VAdDv7DdCdnlDtyQk-DJjGaJF-VFfX9V6WPshYD3AsTxB4BaVe1ayreqeQeAgJV6xFZi3WJVI357zFZ75Ck7TOkHQMkpPGAHbQMCUaxYfzFmGnOYRtNzT324oXjHS0lL4vR7JpfNmPlgRnNNQyH5bcjf-RwpUxx4XOa8RPJ8oMFGM1LiJnOEv_d_UPJbop_pDb-mlM1mxTP2pDN9oue7_4h9_XT25fRzdXl1fnH68bJyuD7OlSIjagVkAbyxtUWJtPa-k9IKhx1YD6bGprYGwYLtoHEOBXZOQtegBzxir7dz5zj9Wsp2PYTkqO_LgdOSdNsWC3UjCyi3oItTSpE6PccwmHinBeiNZL0xqDcGtWr0g2StSuzlbv5iB_L70M5q6b_a9U1ypu-KGBfSHquVKA8LdrLFqLi4CRR1coFGRz7E4l37Kfz_jn8kr5r8</recordid><startdate>19951201</startdate><enddate>19951201</enddate><creator>Cox, Susan M.</creator><creator>Leveno, Kenneth J.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19951201</creationdate><title>Intentional delivery versus expectant management with preterm ruptured membranes at 30–34 weeks' gestation</title><author>Cox, Susan M. ; Leveno, Kenneth J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-9ea1290eb00dab2b343e8ddf44b1c3f0bd0a2352ba30b0bf05cc313fc40f53d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Delivery, Obstetric - methods</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Fetal Membranes, Premature Rupture</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Pregnancy Trimester, Third</topic><topic>Pregnancy. Fetus. Placenta</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cox, Susan M.</creatorcontrib><creatorcontrib>Leveno, Kenneth J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cox, Susan M.</au><au>Leveno, Kenneth J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intentional delivery versus expectant management with preterm ruptured membranes at 30–34 weeks' gestation</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1995-12-01</date><risdate>1995</risdate><volume>86</volume><issue>6</issue><spage>875</spage><epage>879</epage><pages>875-879</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>To determine maternal and neonatal outcomes in pregnancies complicated by preterm rupture of membranes (PROM) at 30–34 weeks' gestation.
A randomized controlled trial was conducted to study the benefits of expectant management in women hospitalized for PROM at 30–34 weeks' gestation. During this investigation, no tocolytics, corticosteroids, or prophylactic antibiotics were used.
Sixty-eight women with PROM were managed expectantly and 61 were delivered intentionally. The mean gestational age at study entry was 31.7 weeks in both the expectant management and intentional delivery groups (
P > .05). The mean gestational ages at delivery were similar (32.0 and 31.7 weeks, respectively). Other indices of pregnancy outcome (ie, birth weight, intraventricular hemorrhage, necrotizing enterocolitis, sepsis, respiratory distress syndrome, and perinatal death) were not significantly improved by expectant management. However, there was a significant increase in the incidence of chorioamnionitis and antepartum hospitalization in the women managed expectantly.
There were no clinically significant neonatal advantages to expectant management of ruptured membranes at 30–34 weeks. Antepartum hospitalization was decreased by 2.5 days in those women randomized to intentional delivery.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7501331</pmid><doi>10.1016/0029-7844(95)00303-9</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 1995-12, Vol.86 (6), p.875-879 |
| issn | 0029-7844 1873-233X |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Biological and medical sciences Delivery, Obstetric - methods Diseases of mother, fetus and pregnancy Female Fetal Membranes, Premature Rupture Gynecology. Andrology. Obstetrics Humans Medical sciences Pregnancy Pregnancy Outcome Pregnancy Trimester, Third Pregnancy. Fetus. Placenta |
| title | Intentional delivery versus expectant management with preterm ruptured membranes at 30–34 weeks' gestation |
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