Retrograde axonal transport of signal transduction proteins in rat sciatic nerve

Neurons require a mechanism to transmit stable signals over the large distance from the nerve growth cone or terminal to the cell body, in order that information from the target tissue can be relayed to the cell body where it is required. Nerve growth factor (NGF), a target-derived neurotrophic fact...

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Veröffentlicht in:	Brain research 1995-08, Vol.690 (1), p.55-63
Hauptverfasser:	Johanson, Sven.O., Crouch, Michael.F., Hendry, Ian A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axonal Transport - physiology Biological and medical sciences Calcium-Calmodulin-Dependent Protein Kinases - metabolism ERK Fundamental and applied biological sciences. Psychology GAP-43 GAP-43 Protein Growth Substances - metabolism Immunohistochemistry Isolated neuron and nerve. Neuroglia MEK MEK kinase Membrane Glycoproteins - metabolism Nerve Growth Factors - metabolism Nerve Tissue Proteins - metabolism Neurotrophic Phosphatidylinositol 3-kinase Phosphorylation Protein-Serine-Threonine Kinases - metabolism Rats Rats, Wistar Retrograde axonal transport Sciatic Nerve - metabolism Signal transduction Signal Transduction - physiology Vertebrates: nervous system and sense organs
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