Triiodothyronine treatment increases substrate cycling between pyruvate carboxylase and malic enzyme in perfused rat liver

The relative roles of pyruvate kinase and malic enzyme in substrate cycling between pyruvate and oxaloacetate were examined in perfused livers of 24-hour—fasted normal and triiodothyronine (T 3)-treated rats using an inhibitor of malic enzyme (hydroxymalonate). Livers were perfused for 60 minutes in...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 1995-11, Vol.44 (11), p.1380-1383
Hauptverfasser:	Petersen, Kitt Falk, Blair, James B., Shulman, Gerald I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine - metabolism Animals Biological and medical sciences Carbohydrates Carbon - metabolism Carbon Isotopes Fundamental and applied biological sciences. Psychology Glucose - metabolism Liver - drug effects Liver - enzymology Liver - metabolism Magnetic Resonance Spectroscopy Malate Dehydrogenase - metabolism Male Metabolisms and neurohumoral controls Oxaloacetates - metabolism Pyruvate Carboxylase - metabolism Pyruvates - metabolism Rats Rats, Sprague-Dawley Tartronates - pharmacology Triiodothyronine - pharmacology Tritium Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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