Preferential TCR V beta 1 gene usage by autoreactive T cells in spontaneous autoimmune thyroiditis of the obese strain of chickens

We studied T cell receptor variable beta (TCR V beta) gene usage by autoreactive T cells in spontaneous autoimmune thyroiditis (SAT) of obese strain (OS) chickens. Chicken alpha beta T cells may express either V beta 1 or V beta 2 genes, the products of which can be recognized by TCR2 and TCR3 monoc...

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Veröffentlicht in:	Journal of autoimmunity 1995-08, Vol.8 (4), p.507-520
Hauptverfasser:	Cihak, J, Hoffmann-Fezer, G, Koller, A, Kaspers, B, Merkle, H, Hála, K, Wick, G, Lösch, U
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology Autoantibodies - biosynthesis Chickens Lymphocyte Depletion Obesity - genetics Obesity - immunology Receptors, Antigen, T-Cell, alpha-beta - genetics Receptors, Antigen, T-Cell, alpha-beta - immunology Receptors, Antigen, T-Cell, gamma-delta - analysis T-Lymphocytes - immunology Thyroglobulin - immunology Thyroid Gland - immunology Thyroiditis, Autoimmune - etiology Thyroiditis, Autoimmune - genetics Thyroiditis, Autoimmune - immunology
Online-Zugang:	Volltext
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