pop-1 Encodes an HMG box protein required for the specification of a mesoderm precursor in Early C. elegans embryos

In C. elegans embryogenesis, the MS blastomere produces predominantly mesodermal cell types, while its sister E generates only endodermal tissue. We show that a maternal gene, pop-1, is essential for the specification of MS fate and that a mutation in pop-1 results in MS adopting an E fate. Previous...

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