Human immunodeficiency virus infection and routine childhood immunisation
Current experience with the safety and efficacy of vaccines in infected children and adults is reviewed to examine the basis for decisions about routine immunisations of children infected with the human immunodeficiency virus (HIV). No adverse reactions to inactivated vaccines have been noted, but c...
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| Veröffentlicht in: | The Lancet (British edition) 1987-09, Vol.2 (8560), p.669-672 |
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| container_end_page | 672 |
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| container_issue | 8560 |
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| container_title | The Lancet (British edition) |
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| creator | von Reyn, C F Clements, C J Mann, J M |
| description | Current experience with the safety and efficacy of vaccines in infected children and adults is reviewed to examine the basis for decisions about routine immunisations of children infected with the human immunodeficiency virus (HIV). No adverse reactions to inactivated vaccines have been noted, but complications with live vaccines have been recorded with both BCG and smallpox. Limited experience with live poliomyelitis and measles vaccines in HIV-infected children has not yet shown any severe complications from these vaccines. Theoretical concerns that immunisation might accelerate the course of HIV infection are not supported by available data. Serological response to most inactivated and live vaccines is reduced in HIV-infected persons, and is related to the degree of immunosuppression present. Preliminary evidence suggests that the severity of some vaccine-preventable diseases is increased in HIV-infected children. This review finds general support for recommendations on immunisation of HIV-infected children that have been developed by the World Health Organisation. |
| format | Article |
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No adverse reactions to inactivated vaccines have been noted, but complications with live vaccines have been recorded with both BCG and smallpox. Limited experience with live poliomyelitis and measles vaccines in HIV-infected children has not yet shown any severe complications from these vaccines. Theoretical concerns that immunisation might accelerate the course of HIV infection are not supported by available data. Serological response to most inactivated and live vaccines is reduced in HIV-infected persons, and is related to the degree of immunosuppression present. Preliminary evidence suggests that the severity of some vaccine-preventable diseases is increased in HIV-infected children. 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This review finds general support for recommendations on immunisation of HIV-infected children that have been developed by the World Health Organisation.</description><subject>Acquired Immunodeficiency Syndrome - complications</subject><subject>Adult</subject><subject>AIDS/HIV</subject><subject>BCG Vaccine - adverse effects</subject><subject>Child</subject><subject>Diphtheria Toxoid - adverse effects</subject><subject>Diphtheria-Tetanus-Pertussis Vaccine</subject><subject>Drug Combinations - adverse effects</subject><subject>Humans</subject><subject>Immunization - adverse effects</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Measles Vaccine - adverse effects</subject><subject>Pertussis Vaccine - adverse effects</subject><subject>Poliovirus Vaccine, Inactivated - adverse effects</subject><subject>Risk</subject><subject>Tetanus Toxoid - adverse effects</subject><subject>Vaccines - adverse effects</subject><subject>Vaccines, Attenuated - immunology</subject><issn>0140-6736</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotz0FrwyAcBXAPG13X7SMUPO0W0GjUHEfZ1kKhl96D0b_UEjWLcdBvv43m9C6_9-A9oDWhnFRCMvGEnnO-EkK4IM0KrWqlZNuQNTrsS9AR-xBKTBacNx6iueEfP5WMfXRgZp8i1tHiKZXZR8Dm4gd7Scneaz7rf_KCHp0eMrwuuUHnz4_zbl8dT1-H3fuxGilTc8Wok0Iow5UxlivV9lJw2nBS88YpCk70ljGnZU95y3vpag5ENNRSK2kLbIPe7rPjlL4L5LkLPhsYBh0hldxJKZSkkv7B7QJLH8B24-SDnm7dcp39AtGmVMw</recordid><startdate>19870919</startdate><enddate>19870919</enddate><creator>von Reyn, C F</creator><creator>Clements, C J</creator><creator>Mann, J M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19870919</creationdate><title>Human immunodeficiency virus infection and routine childhood immunisation</title><author>von Reyn, C F ; Clements, C J ; Mann, J M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p138t-31f7668c48ccd4889b7641540245f81ef6bd33fa7b1494b7f24e0651d1d719e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Acquired Immunodeficiency Syndrome - complications</topic><topic>Adult</topic><topic>AIDS/HIV</topic><topic>BCG Vaccine - adverse effects</topic><topic>Child</topic><topic>Diphtheria Toxoid - adverse effects</topic><topic>Diphtheria-Tetanus-Pertussis Vaccine</topic><topic>Drug Combinations - adverse effects</topic><topic>Humans</topic><topic>Immunization - adverse effects</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Measles Vaccine - adverse effects</topic><topic>Pertussis Vaccine - adverse effects</topic><topic>Poliovirus Vaccine, Inactivated - adverse effects</topic><topic>Risk</topic><topic>Tetanus Toxoid - adverse effects</topic><topic>Vaccines - adverse effects</topic><topic>Vaccines, Attenuated - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>von Reyn, C F</creatorcontrib><creatorcontrib>Clements, C J</creatorcontrib><creatorcontrib>Mann, J M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>von Reyn, C F</au><au>Clements, C J</au><au>Mann, J M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human immunodeficiency virus infection and routine childhood immunisation</atitle><jtitle>The Lancet (British edition)</jtitle><addtitle>Lancet</addtitle><date>1987-09-19</date><risdate>1987</risdate><volume>2</volume><issue>8560</issue><spage>669</spage><epage>672</epage><pages>669-672</pages><issn>0140-6736</issn><abstract>Current experience with the safety and efficacy of vaccines in infected children and adults is reviewed to examine the basis for decisions about routine immunisations of children infected with the human immunodeficiency virus (HIV). No adverse reactions to inactivated vaccines have been noted, but complications with live vaccines have been recorded with both BCG and smallpox. Limited experience with live poliomyelitis and measles vaccines in HIV-infected children has not yet shown any severe complications from these vaccines. Theoretical concerns that immunisation might accelerate the course of HIV infection are not supported by available data. Serological response to most inactivated and live vaccines is reduced in HIV-infected persons, and is related to the degree of immunosuppression present. Preliminary evidence suggests that the severity of some vaccine-preventable diseases is increased in HIV-infected children. This review finds general support for recommendations on immunisation of HIV-infected children that have been developed by the World Health Organisation.</abstract><cop>England</cop><pmid>2887950</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-6736 |
| ispartof | The Lancet (British edition), 1987-09, Vol.2 (8560), p.669-672 |
| issn | 0140-6736 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77687171 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Acquired Immunodeficiency Syndrome - complications Adult AIDS/HIV BCG Vaccine - adverse effects Child Diphtheria Toxoid - adverse effects Diphtheria-Tetanus-Pertussis Vaccine Drug Combinations - adverse effects Humans Immunization - adverse effects Infant Infant, Newborn Male Measles Vaccine - adverse effects Pertussis Vaccine - adverse effects Poliovirus Vaccine, Inactivated - adverse effects Risk Tetanus Toxoid - adverse effects Vaccines - adverse effects Vaccines, Attenuated - immunology |
| title | Human immunodeficiency virus infection and routine childhood immunisation |
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