On the Inhibitory Effect of C17-Sulfoconjugated Catechol Estrogens upon Lipid Peroxidation of Rat Liver Microsomes

The antioxidant effect of C17-sulfoconjugated catechol estrogens was examined under ascorbic acid-or NADPH-dependent lipid peroxidation in rat liver microsomes and compared with that of various estrogens and α-tocopherol. Among the estrogens tested, a free catechol estrogen such as 4-hydroxyestradio...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 1995/08/15, Vol.18(8), pp.1120-1125
Hauptverfasser:	TAKANASHI, Kaori, WATANABE, Kazuhiro, YOSHIZAWA, Itsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	2-hydroxyestradiol 17-sulfate 4-hydroxyestradiol 17-sulfate Animals Antioxidants - pharmacology Aspirin - metabolism Bepridil - analogs & derivatives Bepridil - chemistry Biological and medical sciences Biphenyl Compounds catechol estrogen estrogen antioxidant Estrogens, Catechol - chemistry Estrogens, Catechol - pharmacology Female Free Radicals General and cellular metabolism. Vitamins lipid peroxidation Lipid Peroxidation - drug effects Male Medical sciences Microsomes, Liver - drug effects Microsomes, Liver - metabolism NADP - metabolism Oxidation-Reduction Pharmacology. Drug treatments Picrates Pregnancy Rats Rats, Wistar Sulfur - chemistry
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