Expression of the cyclin‐dependent kinase inhibitors p16INK4, p15INK4B and p21Waf1/cip1 in human breast cancer

Ahderrant cyclin expression has been implicated in oncogenesis in a number of human cancers. Since alterehd function of regulators of cyclin‐dependent kinase (CDK) activity other than cyclins, in particular CDK inhibitors, might play a similar role in oncogenesis, we examined the expression and regu...

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Veröffentlicht in:	International journal of cancer 1995-11, Vol.63 (4), p.584-591
Hauptverfasser:	Musgrove, Elizabeth A., Liuschkis, Richard, Cornish, Ann L., Lee, Christine S. L., Setlur, Vittal, Seshadri, Ram, Sutherland, Robert L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Breast - enzymology Breast - metabolism Breast Neoplasms - enzymology Breast Neoplasms - metabolism Carrier Proteins - biosynthesis Carrier Proteins - genetics Cell Cycle Proteins Cyclin-Dependent Kinase Inhibitor p15 Cyclin-Dependent Kinase Inhibitor p16 Cyclin-Dependent Kinase Inhibitor p21 Cyclin-Dependent Kinases - antagonists & inhibitors Cyclin-Dependent Kinases - genetics Cyclins - biosynthesis Cyclins - genetics Enzyme Inhibitors - metabolism Female Gene Deletion Gene Expression Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Molecular Sequence Data Mutation RNA, Messenger - genetics RNA, Messenger - metabolism Tumor Cells, Cultured Tumor Suppressor Proteins Tumors
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