Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

Retinopathy of prematurity (ROP) is initiated by hyperoxia–induced obliteration of newly formed blood vessels in the retina of the premature newborn. We propose that vessel regression is a consequence of hyperoxia–induced withdrawal of a critical vascular survival factor. We show that regression of...

Ausführliche Beschreibung