Effect of domperidone on cimetidine and ranitidine absorption in rabbits

Cimetidine and ranitidine absorption were studied after oral administration to rabbits, alone or in combination with oral and intravenous domperidone. Blood samples were collected before and 0.25, 0.5, 0.75, 1.0, 1.5, 2.0, 3.0, 4.5, and 6.0h after cimetidine and ranitidine administration. Assays of...

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Veröffentlicht in:	Biopharmaceutics & drug disposition 1987-07, Vol.8 (4), p.319-325
Hauptverfasser:	Al-Khamis, Khalil I., Kaka, Juzar S., Matar, Kamal M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Bioavailability Biological and medical sciences Chromatography, High Pressure Liquid Cimetidine - blood Cimetidine absorption Digestive system Domperidone - pharmacology Domperidone interaction Dose-Response Relationship, Drug Gastric Emptying Injections, Intravenous Male Medical sciences Pharmacology. Drug treatments Rabbits Ranitidine - blood Ranitidine absorption
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