Calcifying disorders of the skin
Calcium is vital to many biologic processes. In skin, it has a profound effect on keratinocyte proliferation, differentiation, and cell-cell adhesion. Serum calcium is tightly regulated by parathyroid hormone and 1,25(OH) 2D 3. Despite this careful regulation, calcification and ossification of cutan...
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Veröffentlicht in: | Journal of the American Academy of Dermatology 1995-11, Vol.33 (5), p.693-706 |
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container_title | Journal of the American Academy of Dermatology |
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creator | Walsh, John S Fairley, Janet A |
description | Calcium is vital to many biologic processes. In skin, it has a profound effect on keratinocyte proliferation, differentiation, and cell-cell adhesion. Serum calcium is tightly regulated by parathyroid hormone and 1,25(OH)
2D
3. Despite this careful regulation, calcification and ossification of cutaneous and subcutaneous tissues may occur. Cutaneous calcification may be divided into four major categories: dystrophic, metastatic, idiopathic, and iatrogenic. Dystrophic calcification occurs as a results of local tissue injury or abnormalities. Metastatic calcification results from abnormal calcium and/or phosphate metabolism. Virtually any process that calcifies may secondarily ossify. Primary ossification may rarely occur. |
doi_str_mv | 10.1016/0190-9622(95)91803-5 |
format | Article |
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2D
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2D
3. Despite this careful regulation, calcification and ossification of cutaneous and subcutaneous tissues may occur. Cutaneous calcification may be divided into four major categories: dystrophic, metastatic, idiopathic, and iatrogenic. Dystrophic calcification occurs as a results of local tissue injury or abnormalities. Metastatic calcification results from abnormal calcium and/or phosphate metabolism. Virtually any process that calcifies may secondarily ossify. Primary ossification may rarely occur.</description><subject>Biological and medical sciences</subject><subject>Calcinosis - etiology</subject><subject>Calcinosis - pathology</subject><subject>Calcinosis - physiopathology</subject><subject>Calcium - physiology</subject><subject>Dermatology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Skin Diseases - etiology</subject><subject>Skin Diseases - pathology</subject><subject>Skin Diseases - physiopathology</subject><subject>Skin involvement in other diseases. Miscellaneous. General aspects</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAUhYMo4zj6DxS6ENFFNWlezUaQwRcMuNF1SJNcjXbaMWmF-fd2nDJLV3dxvnO45yB0SvA1wUTcYKJwrkRRXCp-pUiJac730JRgJXMhS7mPpjvkEB2l9IkxVozKCZpIrqgUYoqyualtgHVo3jMXUhudjylrIes-fJa-QnOMDsDUyZ-Md4beHu5f50_54uXxeX63yC0tRZdzwkghhaNOVBywNFIpEMywiloMHCgxwAihYMGBLSrGKuOAyeENIjgwOkMX29xVbL97nzq9DMn6ujaNb_ukpRRMlUPJGWJb0MY2pehBr2JYmrjWBOvNMHrTWm9aa8X13zCaD7azMb-vlt7tTOMSg34-6iZZU0M0jQ1phxVDDuFywG63mB-2-Ak-6mSDb6x3IXrbadeG___4BTOffPY</recordid><startdate>19951101</startdate><enddate>19951101</enddate><creator>Walsh, John S</creator><creator>Fairley, Janet A</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19951101</creationdate><title>Calcifying disorders of the skin</title><author>Walsh, John S ; Fairley, Janet A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-5141276d3d6b5f07a799f64a4b3c0f5f31af4113fcfdfc2b44badf47937165f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Biological and medical sciences</topic><topic>Calcinosis - etiology</topic><topic>Calcinosis - pathology</topic><topic>Calcinosis - physiopathology</topic><topic>Calcium - physiology</topic><topic>Dermatology</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Skin Diseases - etiology</topic><topic>Skin Diseases - pathology</topic><topic>Skin Diseases - physiopathology</topic><topic>Skin involvement in other diseases. Miscellaneous. General aspects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Walsh, John S</creatorcontrib><creatorcontrib>Fairley, Janet A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Walsh, John S</au><au>Fairley, Janet A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Calcifying disorders of the skin</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>1995-11-01</date><risdate>1995</risdate><volume>33</volume><issue>5</issue><spage>693</spage><epage>706</epage><pages>693-706</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Calcium is vital to many biologic processes. In skin, it has a profound effect on keratinocyte proliferation, differentiation, and cell-cell adhesion. Serum calcium is tightly regulated by parathyroid hormone and 1,25(OH)
2D
3. Despite this careful regulation, calcification and ossification of cutaneous and subcutaneous tissues may occur. Cutaneous calcification may be divided into four major categories: dystrophic, metastatic, idiopathic, and iatrogenic. Dystrophic calcification occurs as a results of local tissue injury or abnormalities. Metastatic calcification results from abnormal calcium and/or phosphate metabolism. Virtually any process that calcifies may secondarily ossify. Primary ossification may rarely occur.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>7593766</pmid><doi>10.1016/0190-9622(95)91803-5</doi><tpages>14</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Biological and medical sciences Calcinosis - etiology Calcinosis - pathology Calcinosis - physiopathology Calcium - physiology Dermatology Humans Medical sciences Skin Diseases - etiology Skin Diseases - pathology Skin Diseases - physiopathology Skin involvement in other diseases. Miscellaneous. General aspects |
title | Calcifying disorders of the skin |
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