STUDIES ON THE METABOLIC FATE OF 14C-ROKITAMYCIN: I. ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION IN RATS

Blood concentrations of 14C-rokitamycin (14C-TMS-19-Q) reached their peaks at 1 hour after a single oral (200 mg/kg) administration to male and female rats, and they were 28.0±0.8 and 24.9±2.0 μg/ml, respectively. No significant differences were observed between male and female in AUC values or maxi...

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Veröffentlicht in:	Japanese journal of antibiotics 1987/03/25, Vol.40(3), pp.499-518
Hauptverfasser:	SUZUKI, TADAKIYO, SAKAI, ATSUSHI, MORISHITA, MASATAKA, MURANISHI, SHOZO
Format:	Artikel
Sprache:	jpn
Schlagworte:	Animals Autoradiography Female Intestinal Absorption Leucomycins - administration & dosage Leucomycins - metabolism Male Miocamycin - analogs & derivatives Rats Rats, Inbred Strains Tissue Distribution
Online-Zugang:	Volltext
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