Murine T cell proliferation can be specifically augmented by macrophages fed with specific antigen: α-2-macroglobulin conjugate

Foreign antigens conjugated to α-2-Macroglobulin (α-2-M) were effectively taken up by murine macrophages via α-2-M receptors. Such effective internalization of α-2-M: antigen conjugate by macrophages resulted in a remarkable increase in its ability to activate murine immune T cells under the followi...

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Veröffentlicht in:	Biochemical and biophysical research communications 1987-07, Vol.146 (1), p.26-31
Hauptverfasser:	Osada, Toshiya, Noro, Nobuhiro, Kuroda, Yoichiro, Ikai, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Macroglobulins - metabolism Animals Antigens - metabolism Applied sciences Exact sciences and technology Leukemia P388 - metabolism Low Density Lipoprotein Receptor-Related Protein-1 Macrophages - immunology Mice Mice, Inbred BALB C Other techniques and industries Receptors, Immunologic - metabolism T-Lymphocytes - cytology
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