Borderline hypertensive autosomal dominant polycystic kidney disease patients have enhanced production of renal dopamine. Normalization of renal haemodynamics by DOPA infusion

In autosomal dominant polycystic kidney disease (ADPKD) the pathophysiology of hypertension, which is frequently observed before loss of renal function, is not well understood. We investigated intrarenal dopamine, the renin-angiotensin-aldosterone system (RAAS), and plasma endothelin in relation to...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 1995, Vol.10 (8), p.1332-1341
Hauptverfasser:	BARENDREGT, J. N. M, FLORIJN, K. W, MUIZERT, Y, CHANG, P. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aldosterone - blood Angiotensin II - administration & dosage Angiotensin-Converting Enzyme Inhibitors - administration & dosage Antihypertensive agents Biological and medical sciences Cardiovascular system Dihydroxyphenylalanine - therapeutic use Dopamine - metabolism Dopamine Agents - therapeutic use Enalaprilat - administration & dosage Endothelins - blood Endothelins - drug effects Female Hemodynamics - drug effects Humans Hypertension, Renal - drug therapy Hypertension, Renal - etiology Hypertension, Renal - metabolism Infusions, Intravenous Male Medical sciences Middle Aged Pharmacology. Drug treatments Polycystic Kidney, Autosomal Dominant - complications Polycystic Kidney, Autosomal Dominant - metabolism Polycystic Kidney, Autosomal Dominant - physiopathology Sodium - urine Sodium, Dietary - administration & dosage
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