Structure of the New Spiroketal-Macrolide A82548A

A new member of the spiroketal-containing macrolide class of fermentation-derived natural products was isolated from mycelial extracts of Streptomyces diastatochromogenes. The principal component, A82548A, was shown to possess a 22-membered macrolide ring system onto which was incorporated both a sp...

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Veröffentlicht in:	Journal of antibiotics 1995/09/25, Vol.48(9), pp.990-996
Hauptverfasser:	KIRST, HERBERT A., LARSEN, STEPHEN H., PASCHAL, JONATHAN W., OCCOLOWITZ, JOHN L., CREEMER, LAWRENCE C., STEINER, JORGE L. RIOS, LOBKOVSKY, EMIL, CLARDY, JON
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Crystallography, X-Ray Fermentation Macrolides - chemistry Macrolides - isolation & purification Magnetic Resonance Spectroscopy Medical sciences Molecular Conformation Molecular Structure Pharmacology. Drug treatments Spiro Compounds - chemistry Spiro Compounds - isolation & purification Stereoisomerism Streptomyces
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