A simple technique for obtaining high quality chromosome preparations from chorionic villus samples using FdU synchronization

A fluorordeoxyuridine (FdU) synchronization technique was applied to 30 chorionic villus samples (CVS) from patients undergoing first trimester fetal diagnosis. The villi were incubated for 15 h in the presence of FdU. The block in DNA synthesis was subsequently released using thymidine and after an...

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Veröffentlicht in:	Prenatal diagnosis 1987-06, Vol.7 (5), p.323-327
Hauptverfasser:	Gibas, Longina M., Grujic, Slobodan, Barr, Marie A., Jackson, Laird G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chorionic Villi Chorionic villi preparation Chromosome Banding Chromosomes, Human - analysis FdU synchronization Female Floxuridine - genetics Genetic Techniques Humans Karyotyping Metaphase Mitotic Index Pregnancy Prenatal Diagnosis - methods
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