Monosialoganglioside cotreatment prevents haloperidol treatment—associated loss of cholinergic enzymes in rat brain

Effects of monosialoganglioside (GM1 ganglioside) cotreatment with haloperidol (HAL) were studied in rat on the haloperidol treatment—associated changes in cholinergic enzymes, choline acetyltransferase (ChAT), and acetvlcholinesterase (AChE) in three brain regions of interest: striatum, hippocampus...

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Veröffentlicht in:	Biological psychiatry (1969) 1995-08, Vol.38 (4), p.246-254
Hauptverfasser:	Mahadik, Sahebarao P., Mukherjee, Sukdeb
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotic Agents - administration & dosage Antipsychotic Agents - analysis Antipsychotic Agents - pharmacology Biological and medical sciences Cerebral Cortex - chemistry Cerebral Cortex - drug effects Cerebral Cortex - enzymology Choline O-Acetyltransferase - metabolism cholinergic neurons Corpus Striatum - chemistry Corpus Striatum - drug effects Corpus Striatum - enzymology Drug toxicity and drugs side effects treatment G(M1) Ganglioside - administration & dosage G(M1) Ganglioside - analysis G(M1) Ganglioside - pharmacology GM1 ganglioside Haloperidol Haloperidol - administration & dosage Haloperidol - analysis Haloperidol - pharmacology hippocampus Hippocampus - chemistry Hippocampus - drug effects Hippocampus - enzymology Male Medical sciences neuroprotection Pharmacology. Drug treatments Rats Rats, Sprague-Dawley striatum Toxicity: nervous system and muscle
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