TIACUMICINS, A NOVEL COMPLEX OF 18-MEMBERED MACROLIDE ANTIBIOTICS: I. TAXONOMY, FERMENTATION AND ANTIBACTERIAL ACTIVITY

A complex of 18-membered macrolide antibiotics has been discovered in the fermentation broth of strain AB718C-41. The producing culture, isolated from a soil sample collected in Hamden, Connecticut, was identified as a strain of Dactylosporangium aurantiacum and was designated D. aurantiacum subsp....

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Veröffentlicht in:	Journal of antibiotics 1987/05/25, Vol.40(5), pp.567-574
Hauptverfasser:	THERIAULT, ROBERT J., KARWOWSKI, JAMES P., JACKSON, MARIANNA, GIROLAMI, ROLAND L., SUNGA, GABRIELA N., VOJTKO, CHARLENE M., COEN, LYLE J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales - analysis Actinomycetales - classification Actinomycetales - physiology Aminoglycosides Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria, Anaerobic - drug effects Biological and medical sciences Biotechnology Carbohydrate Metabolism Fermentation Fidaxomicin Fundamental and applied biological sciences. Psychology Glycosides - analysis Glycosides - isolation & purification Glycosides - pharmacology Gram-Positive Bacteria - drug effects Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Medical sciences Microbial Sensitivity Tests Pharmacology. Drug treatments Production of active biomolecules Soil Microbiology
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