Hemorrhagic shock increases gut macromolecular permeability in the rat

The effect of hemorrhagic shock on gut permeability to macromolecules was investigated using fluorescein isothiocyanate dextrans (4,300 or 73,100 daltons). These were given orally, then measured in systemic blood during hemorrhage (mean arterial pressure of 30 mmHg) and reperfusion; sham-shocked ani...

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Veröffentlicht in:	Shock (Augusta, Ga.) Ga.), 1995-07, Vol.4 (1), p.50-55
Hauptverfasser:	Russell, D H, Barreto, J C, Klemm, K, Miller, T A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - physiology Blood Volume - physiology Dextrans - pharmacokinetics Disease Models, Animal Fluorescein-5-isothiocyanate Gastric Emptying - physiology Hematocrit Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestinal Mucosa - physiopathology Macromolecular Substances Male Permeability Rats Reperfusion Shock, Hemorrhagic - metabolism Shock, Hemorrhagic - pathology Shock, Hemorrhagic - physiopathology
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