Analysis of the mechanism of action of bradykinin on human basilar artery in vitro

Bradykinin (BK) initially produced concentration-related relaxations of human basilar artery in vitro. Concentration-effect curves constructed at 2 h intervals to BK over an 8 h period were reproducible. The rank order of potency of three kinins on the human basilar artery was found to be BK greater...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 1987-04, Vol.335 (4), p.433-437
Hauptverfasser:	WHALLEY, E. T, AMURE, Y. O, LYE, R. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - metabolism basilar artery Basilar Artery - drug effects Biological and medical sciences Blood vessels and receptors bradykinin Bradykinin - pharmacology Endothelium - physiology Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Muscle Relaxation - drug effects Muscle, Smooth, Vascular - drug effects Papaverine - pharmacology Peptidyl-Dipeptidase A - metabolism Vertebrates: cardiovascular system
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