Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty
The purpose of this investigation was to evaluate the relation of coronary artery stenosis and associated pressure gradient to the magnitude of exercise-induced left ventricular dysfunction in patients with single vessel coronary artery disease. The percent stenosis and minimal cross-sectional area...
Gespeichert in:
| Veröffentlicht in: | Journal of the American College of Cardiology 1987-08, Vol.10 (2), p.253-260 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 260 |
|---|---|
| container_issue | 2 |
| container_start_page | 253 |
| container_title | Journal of the American College of Cardiology |
| container_volume | 10 |
| creator | Peterson, Richard J. King, Spencer B. Fajman, William A. Douglas, John S. Grüntzig, Andreas R. Orias, David W. Jones, Robert H. |
| description | The purpose of this investigation was to evaluate the relation of coronary artery stenosis and associated pressure gradient to the magnitude of exercise-induced left ventricular dysfunction in patients with single vessel coronary artery disease. The percent stenosis and minimal cross-sectional area were measured before and after percutaneous transluminal coronary angioplasty and compared with radionuclide measurements of left ventricular function before and after angioplasty in 41 patients with proximal left anterior descending coronary artery lesions, providing 82 points of comparison. The gradient could be measured for 75 comparisons.
Forty stenoses 75% with a mean ejection fraction of 0.49 ± 0.08. Thirty-five stenoses with a gradient 50 mm Hg with a mean ejection fraction of 0.53 ± 0.10.
These data document a relation between the magnitude of coronary artery stenosis and associated gradient to exercise-induced left ventricular dysfunction in homogeneous patient groups. However, discordance of these variables occurs commonly in individual patients. |
| doi_str_mv | 10.1016/S0735-1097(87)80004-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77604010</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0735109787800049</els_id><sourcerecordid>77604010</sourcerecordid><originalsourceid>FETCH-LOGICAL-c423t-e08f1370a52c17b74745f34a93fd9e19e2ef15b72757718cd48744ffe1b75f623</originalsourceid><addsrcrecordid>eNqFkE1rHSEUhqW0pDdpf0LARSnJYhodddRVCaFNAoFCP9biOMfUMldv1QnJov893t7LpbuCcBbneY8vD0KnlHyghA4X34hkoqNEyzMlzxUhhHf6BVpRIVTHhJYv0eqAvEbHpfxqzKCoPkJHjLBB92KF_nyF2daQIk4eu5RTtPkJ21yhjVIhphIKtnHCmwylLBnwfbZTgFhxTRgeIbtQoAtxWhxMOBT3E9bB4hF8avA2aX279s_xeB_SZralPr1Br7ydC7zdzxP04_On71c33d2X69ury7vO8Z7VDojylEliRe-oHCWXXHjGrWZ-0kA19OCpGGUvhZRUuYkrybn3QEcp_NCzE_R-d3eT0-8FSjXrVhTm2UZISzFSDoQTShoodqDLqZQM3mxyWLfWhhKz1W7-ajdbp0a1t9VudMud7j9YxjVMh9Tec9u_2-9tcXb22cam7YCpXvV0GBr2cYdBk_EQIJvimuomNmRw1Uwp_KfIM7zKoRk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77604010</pqid></control><display><type>article</type><title>Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Peterson, Richard J. ; King, Spencer B. ; Fajman, William A. ; Douglas, John S. ; Grüntzig, Andreas R. ; Orias, David W. ; Jones, Robert H.</creator><creatorcontrib>Peterson, Richard J. ; King, Spencer B. ; Fajman, William A. ; Douglas, John S. ; Grüntzig, Andreas R. ; Orias, David W. ; Jones, Robert H.</creatorcontrib><description>The purpose of this investigation was to evaluate the relation of coronary artery stenosis and associated pressure gradient to the magnitude of exercise-induced left ventricular dysfunction in patients with single vessel coronary artery disease. The percent stenosis and minimal cross-sectional area were measured before and after percutaneous transluminal coronary angioplasty and compared with radionuclide measurements of left ventricular function before and after angioplasty in 41 patients with proximal left anterior descending coronary artery lesions, providing 82 points of comparison. The gradient could be measured for 75 comparisons.
Forty stenoses <50% were associated with a mean left ventricular exercise ejection fraction of 0.66 ± 0.08 (mean ± SD), 25 stenoses from 50 to 75% with a mean ejection fraction of 0.59 ± 0.12 and 17 stenoses >75% with a mean ejection fraction of 0.49 ± 0.08. Thirty-five stenoses with a gradient <20 mm Hg were associated with a mean ejection fraction of 0.65 ± 0.09, 24 with a gradient from 20 to 50 mm Hg with a mean ejection fraction of 0.58 ± 0.13 and 16 with a gradient >50 mm Hg with a mean ejection fraction of 0.53 ± 0.10.
These data document a relation between the magnitude of coronary artery stenosis and associated gradient to exercise-induced left ventricular dysfunction in homogeneous patient groups. However, discordance of these variables occurs commonly in individual patients.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/S0735-1097(87)80004-9</identifier><identifier>PMID: 3036925</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Angioplasty, Balloon ; Biological and medical sciences ; Cardiology. Vascular system ; Coronary Circulation ; Coronary Disease - physiopathology ; Coronary Disease - therapy ; Coronary heart disease ; Exercise Test ; Female ; Heart ; Heart Ventricles - diagnostic imaging ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocardial Contraction ; Pressure ; Radionuclide Imaging ; Sodium Pertechnetate Tc 99m ; Stroke Volume</subject><ispartof>Journal of the American College of Cardiology, 1987-08, Vol.10 (2), p.253-260</ispartof><rights>1987 American College of Cardiology Foundation</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-e08f1370a52c17b74745f34a93fd9e19e2ef15b72757718cd48744ffe1b75f623</citedby><cites>FETCH-LOGICAL-c423t-e08f1370a52c17b74745f34a93fd9e19e2ef15b72757718cd48744ffe1b75f623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0735109787800049$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3536,23910,23911,25119,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8282166$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3036925$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Peterson, Richard J.</creatorcontrib><creatorcontrib>King, Spencer B.</creatorcontrib><creatorcontrib>Fajman, William A.</creatorcontrib><creatorcontrib>Douglas, John S.</creatorcontrib><creatorcontrib>Grüntzig, Andreas R.</creatorcontrib><creatorcontrib>Orias, David W.</creatorcontrib><creatorcontrib>Jones, Robert H.</creatorcontrib><title>Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>The purpose of this investigation was to evaluate the relation of coronary artery stenosis and associated pressure gradient to the magnitude of exercise-induced left ventricular dysfunction in patients with single vessel coronary artery disease. The percent stenosis and minimal cross-sectional area were measured before and after percutaneous transluminal coronary angioplasty and compared with radionuclide measurements of left ventricular function before and after angioplasty in 41 patients with proximal left anterior descending coronary artery lesions, providing 82 points of comparison. The gradient could be measured for 75 comparisons.
Forty stenoses <50% were associated with a mean left ventricular exercise ejection fraction of 0.66 ± 0.08 (mean ± SD), 25 stenoses from 50 to 75% with a mean ejection fraction of 0.59 ± 0.12 and 17 stenoses >75% with a mean ejection fraction of 0.49 ± 0.08. Thirty-five stenoses with a gradient <20 mm Hg were associated with a mean ejection fraction of 0.65 ± 0.09, 24 with a gradient from 20 to 50 mm Hg with a mean ejection fraction of 0.58 ± 0.13 and 16 with a gradient >50 mm Hg with a mean ejection fraction of 0.53 ± 0.10.
These data document a relation between the magnitude of coronary artery stenosis and associated gradient to exercise-induced left ventricular dysfunction in homogeneous patient groups. However, discordance of these variables occurs commonly in individual patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Angioplasty, Balloon</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Circulation</subject><subject>Coronary Disease - physiopathology</subject><subject>Coronary Disease - therapy</subject><subject>Coronary heart disease</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Ventricles - diagnostic imaging</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Contraction</subject><subject>Pressure</subject><subject>Radionuclide Imaging</subject><subject>Sodium Pertechnetate Tc 99m</subject><subject>Stroke Volume</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1rHSEUhqW0pDdpf0LARSnJYhodddRVCaFNAoFCP9biOMfUMldv1QnJov893t7LpbuCcBbneY8vD0KnlHyghA4X34hkoqNEyzMlzxUhhHf6BVpRIVTHhJYv0eqAvEbHpfxqzKCoPkJHjLBB92KF_nyF2daQIk4eu5RTtPkJ21yhjVIhphIKtnHCmwylLBnwfbZTgFhxTRgeIbtQoAtxWhxMOBT3E9bB4hF8avA2aX279s_xeB_SZralPr1Br7ydC7zdzxP04_On71c33d2X69ury7vO8Z7VDojylEliRe-oHCWXXHjGrWZ-0kA19OCpGGUvhZRUuYkrybn3QEcp_NCzE_R-d3eT0-8FSjXrVhTm2UZISzFSDoQTShoodqDLqZQM3mxyWLfWhhKz1W7-ajdbp0a1t9VudMud7j9YxjVMh9Tec9u_2-9tcXb22cam7YCpXvV0GBr2cYdBk_EQIJvimuomNmRw1Uwp_KfIM7zKoRk</recordid><startdate>19870801</startdate><enddate>19870801</enddate><creator>Peterson, Richard J.</creator><creator>King, Spencer B.</creator><creator>Fajman, William A.</creator><creator>Douglas, John S.</creator><creator>Grüntzig, Andreas R.</creator><creator>Orias, David W.</creator><creator>Jones, Robert H.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19870801</creationdate><title>Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty</title><author>Peterson, Richard J. ; King, Spencer B. ; Fajman, William A. ; Douglas, John S. ; Grüntzig, Andreas R. ; Orias, David W. ; Jones, Robert H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-e08f1370a52c17b74745f34a93fd9e19e2ef15b72757718cd48744ffe1b75f623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Angioplasty, Balloon</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Circulation</topic><topic>Coronary Disease - physiopathology</topic><topic>Coronary Disease - therapy</topic><topic>Coronary heart disease</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Ventricles - diagnostic imaging</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Contraction</topic><topic>Pressure</topic><topic>Radionuclide Imaging</topic><topic>Sodium Pertechnetate Tc 99m</topic><topic>Stroke Volume</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peterson, Richard J.</creatorcontrib><creatorcontrib>King, Spencer B.</creatorcontrib><creatorcontrib>Fajman, William A.</creatorcontrib><creatorcontrib>Douglas, John S.</creatorcontrib><creatorcontrib>Grüntzig, Andreas R.</creatorcontrib><creatorcontrib>Orias, David W.</creatorcontrib><creatorcontrib>Jones, Robert H.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peterson, Richard J.</au><au>King, Spencer B.</au><au>Fajman, William A.</au><au>Douglas, John S.</au><au>Grüntzig, Andreas R.</au><au>Orias, David W.</au><au>Jones, Robert H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>1987-08-01</date><risdate>1987</risdate><volume>10</volume><issue>2</issue><spage>253</spage><epage>260</epage><pages>253-260</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>The purpose of this investigation was to evaluate the relation of coronary artery stenosis and associated pressure gradient to the magnitude of exercise-induced left ventricular dysfunction in patients with single vessel coronary artery disease. The percent stenosis and minimal cross-sectional area were measured before and after percutaneous transluminal coronary angioplasty and compared with radionuclide measurements of left ventricular function before and after angioplasty in 41 patients with proximal left anterior descending coronary artery lesions, providing 82 points of comparison. The gradient could be measured for 75 comparisons.
Forty stenoses <50% were associated with a mean left ventricular exercise ejection fraction of 0.66 ± 0.08 (mean ± SD), 25 stenoses from 50 to 75% with a mean ejection fraction of 0.59 ± 0.12 and 17 stenoses >75% with a mean ejection fraction of 0.49 ± 0.08. Thirty-five stenoses with a gradient <20 mm Hg were associated with a mean ejection fraction of 0.65 ± 0.09, 24 with a gradient from 20 to 50 mm Hg with a mean ejection fraction of 0.58 ± 0.13 and 16 with a gradient >50 mm Hg with a mean ejection fraction of 0.53 ± 0.10.
These data document a relation between the magnitude of coronary artery stenosis and associated gradient to exercise-induced left ventricular dysfunction in homogeneous patient groups. However, discordance of these variables occurs commonly in individual patients.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3036925</pmid><doi>10.1016/S0735-1097(87)80004-9</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0735-1097 |
| ispartof | Journal of the American College of Cardiology, 1987-08, Vol.10 (2), p.253-260 |
| issn | 0735-1097 1558-3597 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77604010 |
| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Aged Angioplasty, Balloon Biological and medical sciences Cardiology. Vascular system Coronary Circulation Coronary Disease - physiopathology Coronary Disease - therapy Coronary heart disease Exercise Test Female Heart Heart Ventricles - diagnostic imaging Humans Male Medical sciences Middle Aged Myocardial Contraction Pressure Radionuclide Imaging Sodium Pertechnetate Tc 99m Stroke Volume |
| title | Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T05%3A53%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relation%20of%20coronary%20artery%20stenosis%20and%20pressure%20gradient%20to%20exercise-induced%20ischemia%20before%20and%20after%20coronary%20angioplasty&rft.jtitle=Journal%20of%20the%20American%20College%20of%20Cardiology&rft.au=Peterson,%20Richard%20J.&rft.date=1987-08-01&rft.volume=10&rft.issue=2&rft.spage=253&rft.epage=260&rft.pages=253-260&rft.issn=0735-1097&rft.eissn=1558-3597&rft.coden=JACCDI&rft_id=info:doi/10.1016/S0735-1097(87)80004-9&rft_dat=%3Cproquest_cross%3E77604010%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77604010&rft_id=info:pmid/3036925&rft_els_id=S0735109787800049&rfr_iscdi=true |