Myocardial Infarct Imaging in Patients with Technetium–99m 2,3–Dimercaptosuccinic Acid: Superiority of Technetium–99m Pyrophosphate

Technetium–99m 2,3–dimercaptosuccinic acid (Tc–99m DMSA) has been used successfully for imaging acute myocardial infarction in a canine model. The application in humans, however, has not been previously reported. In order to determine the feasibility of using this agent in clinical studies and to co...

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Veröffentlicht in:	Clin. Nucl. Med.; (United States) 1987-07, Vol.12 (7), p.514-518
Hauptverfasser:	LYONS, KENNETH P, MILNE, NORAH, KARLSBERG, RONALD P, OLSON, HAROLD G, KUPERUS, JOHN
Format:	Artikel
Sprache:	eng
Schlagworte:	550601 - Medicine- Unsealed Radionuclides in Diagnostics Aged ANIMALS BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Biological and medical sciences BIOLOGICAL MODELS BODY Cardiology. Vascular system CARDIOVASCULAR DISEASES CARDIOVASCULAR SYSTEM COMPARATIVE EVALUATIONS Coronary heart disease DIAGNOSIS Diphosphates - metabolism DISEASES DOGS DRUGS HEART HOURS LIVING RADIOISOTOPES Humans INTERMEDIATE MASS NUCLEI ISOMERIC NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES Kinetics LABELLED COMPOUNDS Male MAMMALS Medical sciences Middle Aged MUSCLES MYOCARDIAL INFARCTION Myocardial Infarction - diagnostic imaging Myocardial Infarction - metabolism MYOCARDIUM Myocardium - metabolism NUCLEI ODD-EVEN NUCLEI ORGANIC COMPOUNDS ORGANOMETALLIC COMPOUNDS Organometallic Compounds - metabolism ORGANS OXYGEN COMPOUNDS PATIENTS PHOSPHORUS COMPOUNDS PYROPHOSPHATES RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging RADIOPHARMACEUTICALS Species Specificity Succimer - metabolism Sulfhydryl Compounds Technetium - metabolism TECHNETIUM 99 TECHNETIUM ISOTOPES Technetium Tc 99m Dimercaptosuccinic Acid Technetium Tc 99m Pyrophosphate Time Factors VERTEBRATES YEARS LIVING RADIOISOTOPES
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