Accommodation of an Endocapsular Silicone Lens (Phaco-Ersatz ) in the Nonhuman Primate
In owl monkeys, as a model of endocapsular cataract extraction, the lens material was removed through a small hole in the capsule and was replaced with a silicone polymeric gel. The ability of this endocapsular implant (Phaco-Ersatz) to accommodate was documented when pilocarpine produced an increas...
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Veröffentlicht in: | Ophthalmology (Rochester, Minn.) Minn.), 1987-05, Vol.94 (5), p.471-477 |
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container_title | Ophthalmology (Rochester, Minn.) |
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creator | Haefliger, Eduard Parel, Jean-Marie Fantes, Francisco Norton, Edward W.D. Anderson, Douglas R. Forster, Richard K. Hernandez, Eleut Feuer, William J. |
description | In owl monkeys, as a model of endocapsular cataract extraction, the lens material was removed through a small hole in the capsule and was replaced with a silicone polymeric gel. The ability of this endocapsular implant (Phaco-Ersatz) to accommodate was documented when pilocarpine produced an increase in the curvature of the lens surface and a decrease in the anterior chamber depth, just as occurs with the untouched natural lens. Refinements of the surgical technique are required to achieve a controlled degree of filling of the capsular bag and inhibit postoperative epithelial proliferation on the inner capsular surface. |
doi_str_mv | 10.1016/S0161-6420(87)33422-0 |
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The ability of this endocapsular implant (Phaco-Ersatz) to accommodate was documented when pilocarpine produced an increase in the curvature of the lens surface and a decrease in the anterior chamber depth, just as occurs with the untouched natural lens. Refinements of the surgical technique are required to achieve a controlled degree of filling of the capsular bag and inhibit postoperative epithelial proliferation on the inner capsular surface.</description><identifier>ISSN: 0161-6420</identifier><identifier>EISSN: 1549-4713</identifier><identifier>DOI: 10.1016/S0161-6420(87)33422-0</identifier><identifier>PMID: 3601361</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>accommodation ; Accommodation, Ocular ; Animals ; Anterior Chamber - anatomy & histology ; Aotus trivirgatus ; artificial implant ; Cataract Extraction - methods ; cataract surgery ; cholinergic stimulation ; Ciliary Body - drug effects ; endocapsular phacoemulsification ; Lenses, Intraocular ; nonhuman primate ; pachymetry ; Pilocarpine - pharmacology ; Rabbits ; Refraction, Ocular ; Scheimpflug photography ; silicone polymer lens ; Silicones</subject><ispartof>Ophthalmology (Rochester, Minn.), 1987-05, Vol.94 (5), p.471-477</ispartof><rights>1987 American Academy of Ophthalmology, Inc</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-3785d34d50f676503b7bd5fb1dd021188a808e77ca7ef8aa909bb1f00da614533</citedby><cites>FETCH-LOGICAL-c360t-3785d34d50f676503b7bd5fb1dd021188a808e77ca7ef8aa909bb1f00da614533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0161642087334220$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3601361$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haefliger, Eduard</creatorcontrib><creatorcontrib>Parel, Jean-Marie</creatorcontrib><creatorcontrib>Fantes, Francisco</creatorcontrib><creatorcontrib>Norton, Edward W.D.</creatorcontrib><creatorcontrib>Anderson, Douglas R.</creatorcontrib><creatorcontrib>Forster, Richard K.</creatorcontrib><creatorcontrib>Hernandez, Eleut</creatorcontrib><creatorcontrib>Feuer, William J.</creatorcontrib><title>Accommodation of an Endocapsular Silicone Lens (Phaco-Ersatz ) in the Nonhuman Primate</title><title>Ophthalmology (Rochester, Minn.)</title><addtitle>Ophthalmology</addtitle><description>In owl monkeys, as a model of endocapsular cataract extraction, the lens material was removed through a small hole in the capsule and was replaced with a silicone polymeric gel. The ability of this endocapsular implant (Phaco-Ersatz) to accommodate was documented when pilocarpine produced an increase in the curvature of the lens surface and a decrease in the anterior chamber depth, just as occurs with the untouched natural lens. Refinements of the surgical technique are required to achieve a controlled degree of filling of the capsular bag and inhibit postoperative epithelial proliferation on the inner capsular surface.</description><subject>accommodation</subject><subject>Accommodation, Ocular</subject><subject>Animals</subject><subject>Anterior Chamber - anatomy & histology</subject><subject>Aotus trivirgatus</subject><subject>artificial implant</subject><subject>Cataract Extraction - methods</subject><subject>cataract surgery</subject><subject>cholinergic stimulation</subject><subject>Ciliary Body - drug effects</subject><subject>endocapsular phacoemulsification</subject><subject>Lenses, Intraocular</subject><subject>nonhuman primate</subject><subject>pachymetry</subject><subject>Pilocarpine - pharmacology</subject><subject>Rabbits</subject><subject>Refraction, Ocular</subject><subject>Scheimpflug photography</subject><subject>silicone polymer lens</subject><subject>Silicones</subject><issn>0161-6420</issn><issn>1549-4713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMoWqs_QchJ2sNq0myS7Umk1A8oWvDjGrLJLI3sJjXZFfTXu7WlVy8zh5n3fWcehC4ouaKEiuuXvtBM5BMyKuSYsXwyycgBGlCeT7NcUnaIBvuVE3Sa0gchRAiWH6NjJghlgg7Q-60xoWmC1a0LHocKa4_n3gaj16mrdcQvrnYmeMAL8AmPlittQjaPSbc_eIydx-0K8FPwq67ppcvoGt3CGTqqdJ3gfNeH6O1u_jp7yBbP94-z20Vm-gvajMmCW5ZbTiohBSeslKXlVUmtJRNKi0IXpAApjZZQFVpPybQsaUWI1YLmnLEhutz6rmP47CC1qnHJQF1rD6FLSko-lbw3HiK-XTQxpBShUuvNpfFbUaI2PNUfT7WBpQqp_niqje5iF9CVDdi9agewn99s59B_-eUgqmQceAPWRTCtssH9k_ALawyDlg</recordid><startdate>19870501</startdate><enddate>19870501</enddate><creator>Haefliger, Eduard</creator><creator>Parel, Jean-Marie</creator><creator>Fantes, Francisco</creator><creator>Norton, Edward W.D.</creator><creator>Anderson, Douglas R.</creator><creator>Forster, Richard K.</creator><creator>Hernandez, Eleut</creator><creator>Feuer, William J.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19870501</creationdate><title>Accommodation of an Endocapsular Silicone Lens (Phaco-Ersatz ) in the Nonhuman Primate</title><author>Haefliger, Eduard ; 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subjects | accommodation Accommodation, Ocular Animals Anterior Chamber - anatomy & histology Aotus trivirgatus artificial implant Cataract Extraction - methods cataract surgery cholinergic stimulation Ciliary Body - drug effects endocapsular phacoemulsification Lenses, Intraocular nonhuman primate pachymetry Pilocarpine - pharmacology Rabbits Refraction, Ocular Scheimpflug photography silicone polymer lens Silicones |
title | Accommodation of an Endocapsular Silicone Lens (Phaco-Ersatz ) in the Nonhuman Primate |
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