Hypertonic saline resuscitates dogs in endotoxin shock

In this experiment we determined if infusions of hypertonic saline (HS, 1080 Na meq/liter) could resuscitate dogs in endotoxin shock as effectively as Ringer's lactate (RL, 130 Na meq/liter). Anesthetized dogs received iv 0.5 mg/kg of Escherichia coli endotoxin, and mean arterial pressure (MAP,...

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Veröffentlicht in:	The Journal of surgical research 1987-07, Vol.43 (1), p.37-44
Hauptverfasser:	Mullins, Richard J., Hudgens, Russell W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dogs Hemodynamics - drug effects Kidney - drug effects Lymph - drug effects Male Plasma Volume - drug effects Proteins - metabolism Resuscitation - methods Saline Solution, Hypertonic - therapeutic use Shock, Septic - drug therapy Sodium Chloride - therapeutic use Splenectomy
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