IN VITRO ANTIBACTERIAL ACTIVITY AND PHARMACOKINETICS OF OFLOXACIN IN CHRONIC RESPIRATORY TRACT INFECTIONS

Serum and sputum levels of ofloxacin (OFLX) were measured in 5 patients with chronic respiratory tract infections and were compared with antibacterial activity in vitro. 1. Sputum OFLX levels higher than the MIC's against H. influenzae and K. pneumoniae were maintained during the period when da...

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Veröffentlicht in:	Japanese journal of antibiotics 1987/02/25, Vol.40(2), pp.325-330
Hauptverfasser:	SUGIMOTO, YUJI, MATSUMOTO, YUKIO, HITSUDA, YUTAKA, YAMAMOTO, YOSHIMARO, ISHITOBI, KAZUYUKI, SASAKI, TAKAO
Format:	Artikel
Sprache:	jpn
Schlagworte:	Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Bacteria - drug effects Bronchitis - drug therapy Bronchitis - metabolism Bronchitis - microbiology Chronic Disease Drug Resistance, Microbial Humans Ofloxacin Oxazines - metabolism Oxazines - pharmacology Oxazines - therapeutic use Sputum - metabolism
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