Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab
Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusio...
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| Veröffentlicht in: | Circulation (New York, N.Y.) N.Y.), 1987-07, Vol.76 (1), p.181-190 |
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| creator | JOHNSON, L. L LERRICK, K. S COROMILAS, J SELDIN, D. W ESSER, P. D ZIMMERMAN, J. M KELLER, A. M ALDERSON, P. O BIGGER, J. T. JR CANNON, P. J |
| description | Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusion at 2 hr (early reperfusion). Tomographic imaging was performed 24 hr after the intravenous injection of labeled Fab fragments with the use of a dual-head SPECT camera with medium-energy collimators. Immediately after the first tomographic scan, thallium-201 was injected into nine of 12 dogs and imaging was repeated. Estimated infarct size in grams was calculated from transaxially reconstructed, normalized, and background-corrected indium SPECT images with the use of a threshold technique for edge detection. Estimated noninfarcted myocardium in grams was calculated from obliquely reconstructed thallium SPECT images by a similar method. The animals were killed and infarct size in grams and true infarct size as a percentage of total left ventricular myocardial volume were measured by triphenyl tetrazolium chloride staining. Estimated infarct size from indium SPECT images showed an excellent correlation with true infarct size (r = .95, SEE = 4.1 g). Estimated percentage myocardium infarcted was calculated by dividing estimated infarct size from indium images by the sum of estimated infarct size plus estimated noninfarcted myocardium obtained from thallium images. Correlation between the estimated percentage of myocardium infarcted and true percentage of myocardium infarcted was excellent (r = .93, SEE = 4.4%). We conclude that dual-isotope SPECT with indium 111-monoclonal antimyosin antibodies and thallium-201 can accurately estimate infarct size and percentage myocardium infarcted. |
| doi_str_mv | 10.1161/01.CIR.76.1.181 |
| format | Article |
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L ; LERRICK, K. S ; COROMILAS, J ; SELDIN, D. W ; ESSER, P. D ; ZIMMERMAN, J. M ; KELLER, A. M ; ALDERSON, P. O ; BIGGER, J. T. JR ; CANNON, P. J</creator><creatorcontrib>JOHNSON, L. L ; LERRICK, K. S ; COROMILAS, J ; SELDIN, D. W ; ESSER, P. D ; ZIMMERMAN, J. M ; KELLER, A. M ; ALDERSON, P. O ; BIGGER, J. T. JR ; CANNON, P. J ; Columbia Univ., New York, NY</creatorcontrib><description>Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusion at 2 hr (early reperfusion). Tomographic imaging was performed 24 hr after the intravenous injection of labeled Fab fragments with the use of a dual-head SPECT camera with medium-energy collimators. Immediately after the first tomographic scan, thallium-201 was injected into nine of 12 dogs and imaging was repeated. Estimated infarct size in grams was calculated from transaxially reconstructed, normalized, and background-corrected indium SPECT images with the use of a threshold technique for edge detection. Estimated noninfarcted myocardium in grams was calculated from obliquely reconstructed thallium SPECT images by a similar method. The animals were killed and infarct size in grams and true infarct size as a percentage of total left ventricular myocardial volume were measured by triphenyl tetrazolium chloride staining. Estimated infarct size from indium SPECT images showed an excellent correlation with true infarct size (r = .95, SEE = 4.1 g). Estimated percentage myocardium infarcted was calculated by dividing estimated infarct size from indium images by the sum of estimated infarct size plus estimated noninfarcted myocardium obtained from thallium images. Correlation between the estimated percentage of myocardium infarcted and true percentage of myocardium infarcted was excellent (r = .93, SEE = 4.4%). We conclude that dual-isotope SPECT with indium 111-monoclonal antimyosin antibodies and thallium-201 can accurately estimate infarct size and percentage myocardium infarcted.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/01.CIR.76.1.181</identifier><identifier>PMID: 2439232</identifier><identifier>CODEN: CIRCAZ</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; ANIMALS ; ANTIBODIES ; Antibodies, Monoclonal - immunology ; BETA DECAY RADIOISOTOPES ; Biological and medical sciences ; BODY ; Cardiology. Vascular system ; CARDIOVASCULAR DISEASES ; CARDIOVASCULAR SYSTEM ; COLLIMATORS ; COMPUTERIZED TOMOGRAPHY ; Coronary heart disease ; DAYS LIVING RADIOISOTOPES ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DISEASES ; DOGS ; ELECTRON CAPTURE RADIOISOTOPES ; EMISSION COMPUTED TOMOGRAPHY ; GLOBULINS ; HEART ; HEAVY NUCLEI ; Immunoglobulin Fab Fragments - immunology ; Indium ; INDIUM 111 ; INDIUM ISOTOPES ; INTERMEDIATE MASS NUCLEI ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; Male ; MAMMALS ; Medical sciences ; MINUTES LIVING RADIOISOTOPES ; MONOCLONAL ANTIBODIES ; MYOCARDIAL INFARCTION ; Myocardial Infarction - diagnostic imaging ; MYOSIN ; Myosins - immunology ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANIC COMPOUNDS ; ORGANS ; PERFUSED ORGANS ; PROTEINS ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; SECONDS LIVING RADIOISOTOPES ; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY ; Staining and Labeling ; Tetrazolium Salts ; Thallium ; THALLIUM 201 ; THALLIUM ISOTOPES ; TOMOGRAPHY ; Tomography, Emission-Computed ; VERTEBRATES</subject><ispartof>Circulation (New York, N.Y.), 1987-07, Vol.76 (1), p.181-190</ispartof><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3441-455e0befe68fcebd909881aa16ead2ee16fe8bd6cf777e27b636058286cc7ec83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,881,3674,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8327117$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2439232$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6277331$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>JOHNSON, L. L</creatorcontrib><creatorcontrib>LERRICK, K. S</creatorcontrib><creatorcontrib>COROMILAS, J</creatorcontrib><creatorcontrib>SELDIN, D. W</creatorcontrib><creatorcontrib>ESSER, P. D</creatorcontrib><creatorcontrib>ZIMMERMAN, J. M</creatorcontrib><creatorcontrib>KELLER, A. M</creatorcontrib><creatorcontrib>ALDERSON, P. O</creatorcontrib><creatorcontrib>BIGGER, J. T. JR</creatorcontrib><creatorcontrib>CANNON, P. J</creatorcontrib><creatorcontrib>Columbia Univ., New York, NY</creatorcontrib><title>Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab</title><title>Circulation (New York, N.Y.)</title><addtitle>Circulation</addtitle><description>Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusion at 2 hr (early reperfusion). Tomographic imaging was performed 24 hr after the intravenous injection of labeled Fab fragments with the use of a dual-head SPECT camera with medium-energy collimators. Immediately after the first tomographic scan, thallium-201 was injected into nine of 12 dogs and imaging was repeated. Estimated infarct size in grams was calculated from transaxially reconstructed, normalized, and background-corrected indium SPECT images with the use of a threshold technique for edge detection. Estimated noninfarcted myocardium in grams was calculated from obliquely reconstructed thallium SPECT images by a similar method. The animals were killed and infarct size in grams and true infarct size as a percentage of total left ventricular myocardial volume were measured by triphenyl tetrazolium chloride staining. Estimated infarct size from indium SPECT images showed an excellent correlation with true infarct size (r = .95, SEE = 4.1 g). Estimated percentage myocardium infarcted was calculated by dividing estimated infarct size from indium images by the sum of estimated infarct size plus estimated noninfarcted myocardium obtained from thallium images. Correlation between the estimated percentage of myocardium infarcted and true percentage of myocardium infarcted was excellent (r = .93, SEE = 4.4%). We conclude that dual-isotope SPECT with indium 111-monoclonal antimyosin antibodies and thallium-201 can accurately estimate infarct size and percentage myocardium infarcted.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>ANIMALS</subject><subject>ANTIBODIES</subject><subject>Antibodies, Monoclonal - immunology</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>Biological and medical sciences</subject><subject>BODY</subject><subject>Cardiology. Vascular system</subject><subject>CARDIOVASCULAR DISEASES</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>COLLIMATORS</subject><subject>COMPUTERIZED TOMOGRAPHY</subject><subject>Coronary heart disease</subject><subject>DAYS LIVING RADIOISOTOPES</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DISEASES</subject><subject>DOGS</subject><subject>ELECTRON CAPTURE RADIOISOTOPES</subject><subject>EMISSION COMPUTED TOMOGRAPHY</subject><subject>GLOBULINS</subject><subject>HEART</subject><subject>HEAVY NUCLEI</subject><subject>Immunoglobulin Fab Fragments - immunology</subject><subject>Indium</subject><subject>INDIUM 111</subject><subject>INDIUM ISOTOPES</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>Male</subject><subject>MAMMALS</subject><subject>Medical sciences</subject><subject>MINUTES LIVING RADIOISOTOPES</subject><subject>MONOCLONAL ANTIBODIES</subject><subject>MYOCARDIAL INFARCTION</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>MYOSIN</subject><subject>Myosins - immunology</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANIC COMPOUNDS</subject><subject>ORGANS</subject><subject>PERFUSED ORGANS</subject><subject>PROTEINS</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>SECONDS LIVING RADIOISOTOPES</subject><subject>SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY</subject><subject>Staining and Labeling</subject><subject>Tetrazolium Salts</subject><subject>Thallium</subject><subject>THALLIUM 201</subject><subject>THALLIUM ISOTOPES</subject><subject>TOMOGRAPHY</subject><subject>Tomography, Emission-Computed</subject><subject>VERTEBRATES</subject><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kUFv1DAQhSMEKqVw5oRkIcSp2XrsjZ09ohWFSkVICM7WxJnsGiV2sB2h5bfx4_B2l5481vvmjT2vql4DXwEouOGw2t59W2m1ghW08KS6hEas63UjN0-rS875ptZSiOfVi5R-lquSurmoLsRaboQUl9XfL4RpiTSRzywMzPkBo80suT_E0PdspmiLhjti0yFYjL1bpv8Y9aViyPqwY3OkGSNmFzz77fK-WPjdSGzehxx8TZNL6ajZMM3LsTOHKewizvvDNct7HMdiXAsO1w9znX8YBAD1FHywY_A4FiW78oxizW6xe1k9G3BM9Op8XlU_bj9-336u779-utt-uK-tXK-hLKMh3tFAqh0sdf2Gb9oWEEER9oII1EBt1ys7aK1J6E5JxZtWtMpaTbaVV9Xbk29I2ZlkXSa7t8F7stkoobWUUKD3J2iO4ddCKZvyY0vjiJ7CkozWTQtc8gLenEAbQ0qRBjNHN2E8GODmGKrhYEqoRisDpoRaOt6crZduov6RP6dY9HdnHZPFcYjorUuPWCuFBtDyH3HHrbQ</recordid><startdate>198707</startdate><enddate>198707</enddate><creator>JOHNSON, L. L</creator><creator>LERRICK, K. S</creator><creator>COROMILAS, J</creator><creator>SELDIN, D. W</creator><creator>ESSER, P. D</creator><creator>ZIMMERMAN, J. M</creator><creator>KELLER, A. M</creator><creator>ALDERSON, P. O</creator><creator>BIGGER, J. T. JR</creator><creator>CANNON, P. J</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>198707</creationdate><title>Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab</title><author>JOHNSON, L. L ; LERRICK, K. S ; COROMILAS, J ; SELDIN, D. W ; ESSER, P. D ; ZIMMERMAN, J. M ; KELLER, A. M ; ALDERSON, P. O ; BIGGER, J. T. JR ; CANNON, P. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3441-455e0befe68fcebd909881aa16ead2ee16fe8bd6cf777e27b636058286cc7ec83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>ANIMALS</topic><topic>ANTIBODIES</topic><topic>Antibodies, Monoclonal - immunology</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>Biological and medical sciences</topic><topic>BODY</topic><topic>Cardiology. Vascular system</topic><topic>CARDIOVASCULAR DISEASES</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>COLLIMATORS</topic><topic>COMPUTERIZED TOMOGRAPHY</topic><topic>Coronary heart disease</topic><topic>DAYS LIVING RADIOISOTOPES</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DISEASES</topic><topic>DOGS</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>EMISSION COMPUTED TOMOGRAPHY</topic><topic>GLOBULINS</topic><topic>HEART</topic><topic>HEAVY NUCLEI</topic><topic>Immunoglobulin Fab Fragments - immunology</topic><topic>Indium</topic><topic>INDIUM 111</topic><topic>INDIUM ISOTOPES</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>Male</topic><topic>MAMMALS</topic><topic>Medical sciences</topic><topic>MINUTES LIVING RADIOISOTOPES</topic><topic>MONOCLONAL ANTIBODIES</topic><topic>MYOCARDIAL INFARCTION</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>MYOSIN</topic><topic>Myosins - immunology</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANIC COMPOUNDS</topic><topic>ORGANS</topic><topic>PERFUSED ORGANS</topic><topic>PROTEINS</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>SECONDS LIVING RADIOISOTOPES</topic><topic>SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY</topic><topic>Staining and Labeling</topic><topic>Tetrazolium Salts</topic><topic>Thallium</topic><topic>THALLIUM 201</topic><topic>THALLIUM ISOTOPES</topic><topic>TOMOGRAPHY</topic><topic>Tomography, Emission-Computed</topic><topic>VERTEBRATES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JOHNSON, L. L</creatorcontrib><creatorcontrib>LERRICK, K. S</creatorcontrib><creatorcontrib>COROMILAS, J</creatorcontrib><creatorcontrib>SELDIN, D. W</creatorcontrib><creatorcontrib>ESSER, P. D</creatorcontrib><creatorcontrib>ZIMMERMAN, J. M</creatorcontrib><creatorcontrib>KELLER, A. M</creatorcontrib><creatorcontrib>ALDERSON, P. O</creatorcontrib><creatorcontrib>BIGGER, J. T. JR</creatorcontrib><creatorcontrib>CANNON, P. J</creatorcontrib><creatorcontrib>Columbia Univ., New York, NY</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JOHNSON, L. L</au><au>LERRICK, K. S</au><au>COROMILAS, J</au><au>SELDIN, D. W</au><au>ESSER, P. D</au><au>ZIMMERMAN, J. M</au><au>KELLER, A. M</au><au>ALDERSON, P. O</au><au>BIGGER, J. T. JR</au><au>CANNON, P. J</au><aucorp>Columbia Univ., New York, NY</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><addtitle>Circulation</addtitle><date>1987-07</date><risdate>1987</risdate><volume>76</volume><issue>1</issue><spage>181</spage><epage>190</epage><pages>181-190</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><coden>CIRCAZ</coden><abstract>Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusion at 2 hr (early reperfusion). Tomographic imaging was performed 24 hr after the intravenous injection of labeled Fab fragments with the use of a dual-head SPECT camera with medium-energy collimators. Immediately after the first tomographic scan, thallium-201 was injected into nine of 12 dogs and imaging was repeated. Estimated infarct size in grams was calculated from transaxially reconstructed, normalized, and background-corrected indium SPECT images with the use of a threshold technique for edge detection. Estimated noninfarcted myocardium in grams was calculated from obliquely reconstructed thallium SPECT images by a similar method. The animals were killed and infarct size in grams and true infarct size as a percentage of total left ventricular myocardial volume were measured by triphenyl tetrazolium chloride staining. Estimated infarct size from indium SPECT images showed an excellent correlation with true infarct size (r = .95, SEE = 4.1 g). Estimated percentage myocardium infarcted was calculated by dividing estimated infarct size from indium images by the sum of estimated infarct size plus estimated noninfarcted myocardium obtained from thallium images. Correlation between the estimated percentage of myocardium infarcted and true percentage of myocardium infarcted was excellent (r = .93, SEE = 4.4%). We conclude that dual-isotope SPECT with indium 111-monoclonal antimyosin antibodies and thallium-201 can accurately estimate infarct size and percentage myocardium infarcted.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>2439232</pmid><doi>10.1161/01.CIR.76.1.181</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-7322 |
| ispartof | Circulation (New York, N.Y.), 1987-07, Vol.76 (1), p.181-190 |
| issn | 0009-7322 1524-4539 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77581030 |
| source | MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics ANIMALS ANTIBODIES Antibodies, Monoclonal - immunology BETA DECAY RADIOISOTOPES Biological and medical sciences BODY Cardiology. Vascular system CARDIOVASCULAR DISEASES CARDIOVASCULAR SYSTEM COLLIMATORS COMPUTERIZED TOMOGRAPHY Coronary heart disease DAYS LIVING RADIOISOTOPES DIAGNOSIS DIAGNOSTIC TECHNIQUES DISEASES DOGS ELECTRON CAPTURE RADIOISOTOPES EMISSION COMPUTED TOMOGRAPHY GLOBULINS HEART HEAVY NUCLEI Immunoglobulin Fab Fragments - immunology Indium INDIUM 111 INDIUM ISOTOPES INTERMEDIATE MASS NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES Male MAMMALS Medical sciences MINUTES LIVING RADIOISOTOPES MONOCLONAL ANTIBODIES MYOCARDIAL INFARCTION Myocardial Infarction - diagnostic imaging MYOSIN Myosins - immunology NUCLEI ODD-EVEN NUCLEI ORGANIC COMPOUNDS ORGANS PERFUSED ORGANS PROTEINS RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE SECONDS LIVING RADIOISOTOPES SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY Staining and Labeling Tetrazolium Salts Thallium THALLIUM 201 THALLIUM ISOTOPES TOMOGRAPHY Tomography, Emission-Computed VERTEBRATES |
| title | Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T04%3A06%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Measurement%20of%20infarct%20size%20and%20percentage%20myocardium%20infarcted%20in%20a%20dog%20preparation%20with%20single%20photon-emission%20computed%20tomography,%20thallium-201,%20and%20indium%20111-monoclonal%20antimyosin%20Fab&rft.jtitle=Circulation%20(New%20York,%20N.Y.)&rft.au=JOHNSON,%20L.%20L&rft.aucorp=Columbia%20Univ.,%20New%20York,%20NY&rft.date=1987-07&rft.volume=76&rft.issue=1&rft.spage=181&rft.epage=190&rft.pages=181-190&rft.issn=0009-7322&rft.eissn=1524-4539&rft.coden=CIRCAZ&rft_id=info:doi/10.1161/01.CIR.76.1.181&rft_dat=%3Cproquest_osti_%3E77581030%3C/proquest_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77581030&rft_id=info:pmid/2439232&rfr_iscdi=true |