A comparative 1H-N.M.R. study of MurNAc- l-Ala- d-iGln (MDP) and its analogue murabutide: Evidence for a structure involving two successive β-turns in MDP

The active principle, MurNAc- l-Ala- d-iGln (MDP), of complete Freund's adjuvant and its analogue, MurNAc- l-Ala- d-Gln-O nBu (murabutide), which express immunomodulatory as well as other biological properties, have been studied by 2D- 1H-n.m.r. spectroscopy at 500 MHz. The results suggest the...

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Veröffentlicht in:	Carbohydrate research 1987-04, Vol.162 (1), p.23-32
Hauptverfasser:	Fermandjian, Serge, Perly, Bruno, Level, Michel, Lefrancier, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylmuramyl-Alanyl-Isoglutamine - analogs & derivatives Carbohydrate Conformation Glycopeptides Magnetic Resonance Spectroscopy - methods Protein Conformation Structure-Activity Relationship Thermodynamics
Online-Zugang:	Volltext
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