Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities

Although progesterone has been recognized as essential for the establishment and maintenance of pregnancy, this steroid hormone has been recently implicated to have a functional role in a number of other reproductive events. The physiological effects of progesterone are mediated by the progesterone...

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Veröffentlicht in:	Genes & development 1995-09, Vol.9 (18), p.2266-2278
Hauptverfasser:	Lydon, J P, DeMayo, F J, Funk, C R, Mani, S K, Hughes, A R, Montgomery, Jr, C A, Shyamala, G, Conneely, O M, O'Malley, B W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chimera Copulation - drug effects Decidua - physiology Estrogens - pharmacology Female Gene Targeting Genitalia, Female - drug effects Genitalia, Female - physiopathology Homozygote Male Mammary Glands, Animal - drug effects Mammary Glands, Animal - physiopathology Mice Mice, Mutant Strains Ovulation Progesterone - pharmacology Receptors, Progesterone - deficiency Receptors, Progesterone - genetics Reproduction - physiology Sex Characteristics Uterus - drug effects
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