The role of fs(1)K10 in the localization of the mRNA of the TGFα homolog gurken within the Drosophila oocyte

A critical step in Drosophila dorsoventral patterning is the movement of gurken mRNA from the anterior cortex of the oocyte to the oocyte's anterodorsal corner at stage 8 of oogenesis. Such movement is dependent on fs(1)K10. It has been proposed that fs(1)K10 mediates gurken mRNA movement by do...

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Veröffentlicht in:	Mechanisms of development 1995-06, Vol.51 (2), p.183-192
Hauptverfasser:	Serano, Thomas L., Karlin-McGinness, Michelle, Cohen, Robert S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Polarity Dorsoventral patterning Down-Regulation Drosophila - genetics Drosophila - growth & development Drosophila - metabolism Drosophila grk gene Drosophila K10 gene Drosophila oogenesis Drosophila Proteins Female Genes, Insect Insect Hormones - genetics Male mRNA localization Mutation Oocytes - metabolism Oogenesis Pattern formation RNA, Messenger - genetics RNA, Messenger - metabolism Transforming Growth Factor alpha - genetics Transforming Growth Factors - genetics
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