Heavy-metal mitogenesis: Thymocyte activation by ZN ++ requires 2-mercaptoethanol and lipopolysaccharide as cofactors

Thymocytes from Balb/C mice were activated in vitro by Zn ++ as noted by the several-foldincreases in 3H-thymidine incorporation at 144 h of culture. Thymocyte activation by Zn ++ required the presence of 2-mercaptoethanol (2-ME) and bacterial lipopolysaccharide (LPS) in concentrations as low as 1.0...

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Veröffentlicht in:	Immunobiology (1979) 1987-03, Vol.174 (2), p.233-243
Hauptverfasser:	Reardon, C.L., Lucas, D.O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals In Vitro Techniques Lipopolysaccharides - pharmacology Lymphocyte Activation - drug effects Mercaptoethanol - pharmacology Mercury - pharmacology Mice Mice, Inbred BALB C Mitogens T-Lymphocytes - drug effects T-Lymphocytes - immunology Zinc - pharmacology
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