Contribution of IL-1, CD14, and CD13 in the increased IL-6 production induced by in vitro monocyte-synoviocyte interactions

Rheumatoid synovitis is characterized by an infiltration of mononuclear cells and by the proliferation of synoviocytes. Monocytes and synoviocytes are major producers of cytokines, growth factors, and enzymes that contribute to the rheumatoid arthritis (RA) process. Since they are in close contact i...

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Veröffentlicht in:	The Journal of immunology (1950) 1995-10, Vol.155 (7), p.3645-3652
Hauptverfasser:	Chomarat, P, Rissoan, MC, Pin, JJ, Banchereau, J, Miossec, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - immunology CD13 Antigens - pharmacology Cell Aggregation Fibroblasts - cytology Fibroblasts - immunology Humans Interleukin-1 - pharmacology Interleukin-6 - biosynthesis Lipopolysaccharide Receptors - pharmacology Monocytes - cytology Monocytes - immunology Synovial Membrane - cytology Synovial Membrane - immunology
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