A 2.4-Megabase Physical Map Spanning the CYP2C Gene Cluster on Chromosome 10q24

The CYP2C gene cluster on chromosome 10q24 encodes the P450IIC enzymes, members of the cytochrome P450 monooxygenase superfamily. The P450-IIC enzymes are required for the metabolism of a number of foreign compounds, including the drugs mephenytoin and tolbutamide, and are also thought to be involve...

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Veröffentlicht in:	Genomics 1995-07, Vol.28 (2), p.328-332
Hauptverfasser:	Gray, Ian C., Nobile, Carlo, Muresu, Rosella, Ford, Sally, Spurr, Nigel K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aryl Hydrocarbon Hydroxylases Base Sequence Biological and medical sciences BIOLOGICAL MARKERS BIOLOGY AND MEDICINE, BASIC STUDIES Chromosome Mapping Chromosomes, Human, Pair 10 Classical genetics, quantitative genetics, hybrids Cytochrome P-450 CYP2C8 Cytochrome P-450 CYP2C9 Cytochrome P-450 Enzyme System - genetics DNA SEQUENCING DNA-CLONING ELECTROPHORESIS ENZYMES Fundamental and applied biological sciences. Psychology GENES GENETIC MAPPING Genetics of eukaryotes. Biological and molecular evolution Human HUMAN CHROMOSOMES Humans METABOLISM Molecular Sequence Data Multigene Family POLYMERASE CHAIN REACTION Retinol-Binding Proteins - genetics Sequence Tagged Sites Steroid 16-alpha-Hydroxylase STEROID HORMONES Steroid Hydroxylases - genetics STRUCTURE-ACTIVITY RELATIONSHIPS
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